Evidence map›Paper›PMID 41523179›Full record

ArticleRespirology case reports2026

Isolated Mediastinal and Hilar Lymphadenopathy as a Manifestation of IgG4-Related Disease Diagnosed by EBUS-Guided Transbronchial Mediastinal Cryobiopsy.

Wen Zhang, Zansheng Huang, Lei Zhou, Hanxiang Song, Mingzhou Zhang, Guansong Wang, Ye Fan, Zhi Xu

Abstract read
In one paragraph

Article in Respirology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wen ZhangInstitute of Respiratory Diseases, Department of Pulmonary and Critical Care Medicine Xinqiao Hospital, Army Medical University Chongqing China.ORCID https://orcid.org/0000-0002-7122-8606
Zansheng HuangInstitute of Respiratory Diseases, Department of Pulmonary and Critical Care Medicine Xinqiao Hospital, Army Medical University Chongqing China.
Lei ZhouThe First People's Hospital of Kaili Kaili Guizhou China.
Hanxiang SongDepartment of Pathology Xinqiao Hospital, Army Medical University Chongqing China.
Mingzhou ZhangInstitute of Respiratory Diseases, Department of Pulmonary and Critical Care Medicine Xinqiao Hospital, Army Medical University Chongqing China.
Guansong WangInstitute of Respiratory Diseases, Department of Pulmonary and Critical Care Medicine Xinqiao Hospital, Army Medical University Chongqing China.
Ye FanInstitute of Respiratory Diseases, Department of Pulmonary and Critical Care Medicine Xinqiao Hospital, Army Medical University Chongqing China.
Zhi XuInstitute of Respiratory Diseases, Department of Pulmonary and Critical Care Medicine Xinqiao Hospital, Army Medical University Chongqing China.ORCID https://orcid.org/0000-0003-1199-6635

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunoglobulin G4-related disease (IgG4-RD) is a fibroinflammatory condition that can involve multiple organs, including mediastinal lesions. Transbronchial mediastinal cryobiopsy has recently emerged as a novel sampling technique that improves diagnostic yield for mediastinal lesions, particularly in rare tumours and benign disorders, compared to endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). Here we report a case of IgG4-RD presenting with hilar and mediastinal lymphadenopathy successfully diagnosed by transbronchial mediastinal cryobiopsy using a ø1.7 mm cryoprobe. The diagnosis was established in accordance with the 2020 revised comprehensive diagnostic criteria for IgG4-RD, after exclusion of infectious and lymphoproliferative disorders. Endoscopic mediastinal cryobiopsy may represent a valuable and minimally invasive strategy for diagnosing mediastinal diseases.

Indexed as

cryobiopsyendoscopic ultrasoundIgG4‐related disease

Identifiers

PMID41523179
PMCPMC12779465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.