Evidence map›Paper›PMID 41523177›Full record

ArticleJournal of current glaucoma practice

Surgical Outcome Comparison of Open Conjunctival

Serina S Applebaum, Addiskidan Hundito, Christopher C Teng, Soshian Sarrafpour, Ji Liu

Abstract read
In one paragraph

Article in Journal of current glaucoma practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Serina S ApplebaumYale University School of Medicine, New Haven, Connecticut, United States.
Addiskidan HunditoYale University School of Medicine, New Haven, Connecticut, United States.
Christopher C TengDepartment of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Connecticut, United States.
Soshian SarrafpourDepartment of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Connecticut, United States.
Ji LiuDepartment of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Connecticut, United States.

Funding

NIA Short Term Research Training: Students in Health Professional SchoolsT35AG049685 · NIA · YALE UNIVERSITY · PI Sarwat I Chaudhry, Terri R. Fried · 2016 to 2026
$804k
NIA NIH HHS T35 AG049685
6 · The paper itself

Abstract

Aim: To evaluate the safety, efficacy, and risk factors for failure compared between trabeculectomy and open conjunctival Methods: For this retrospective single-center study, we included eyes of patients >18 years old with open-angle glaucoma and baseline intraocular pressure (IOP) >17 mm Hg who received trabeculectomy or XGS AEO placement. We excluded aphakic eyes and those missing preoperative data. The primary outcome was the rate of success (6 ≤ IOP ≤ 21 mm Hg, plus ≥20% IOP reduction from baseline, with or without ocular hypotensive medications) after 1 year, compared between groups. Alternative IOP upper limits were 18 and 15 mm Hg. Secondary outcomes were risk factors for failure, complications, and postoperative interventions. Results: We studied 82 trabeculectomy eyes and 34 XGS AEO eyes. At 1 year, 62%, 61%, and 49% of trabeculectomy eyes and 72%, 69%, and 31% of XGS AEO eyes achieved success using IOP upper limits of 21, 18, and 15 mm Hg, respectively. There were no 1-year intergroup differences in IOP, IOP percent change, visual acuity, complications, or revision surgeries. Medication use was higher in the XGS AEO group. Prior trabeculoplasty was associated with a lower risk for failure in the XGS AEO group, but an increased risk in the trabeculectomy group. More eyes in the trabeculectomy group underwent manipulations postoperatively ( Conclusion: Open conjunctival Clinical significance: The similar outcomes and fewer postoperative manipulations of XGS AEO implantation compared to trabeculectomy make it a reasonable surgical option in open-angle glaucoma. How to cite this article: Applebaum SS, Hundito A, Teng CC,

Indexed as

Ab externo gel stentCohort studyGlaucoma surgeryMicroinvasive glaucoma surgeriesRefractory glaucomaTrabeculectomy

Identifiers

PMID41523177
PMCPMC12780353

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.