Evidence map›Paper›PMID 41523143›Full record

ArticleImmune network2025

Mitochondria Derived From iPSCs Control by Reciprocal Regulation of Th17/Treg and Anti-Fibrosis.

Jin Seok Woo, Hanbi Lee, JooYeon Jhun, SeungCheon Yang, Yeon Su Lee, Yoo-Jin Shin, Sun Woo Lim, Bo-In Lee, Chul Woo Yang, Byung Ha Chung and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Immune network, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jin Seok WooLab of Translational ImmunoMedicine, Catholic Research Institute of Medical Science, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID https://orcid.org/0000-0001-8921-2832
Hanbi LeeDivision of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID https://orcid.org/0000-0001-7326-0602
JooYeon JhunLab of Translational ImmunoMedicine, Catholic Research Institute of Medical Science, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID https://orcid.org/0000-0003-3953-669X
SeungCheon YangLab of Translational ImmunoMedicine, Catholic Research Institute of Medical Science, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID https://orcid.org/0009-0005-6336-0999
Yeon Su LeeLab of Translational ImmunoMedicine, Catholic Research Institute of Medical Science, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID https://orcid.org/0009-0007-1685-6099
Yoo-Jin ShinTransplant Research Center, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID https://orcid.org/0000-0003-1922-9369
Sun Woo LimTransplant Research Center, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID https://orcid.org/0000-0003-4386-6819
Bo-In LeeDivision of Gastroenterology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID https://orcid.org/0000-0002-0218-4136
Chul Woo YangDivision of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID https://orcid.org/0000-0001-9796-636X
Byung Ha ChungDivision of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID https://orcid.org/0000-0003-0048-5717
Mi-La ChoLab of Translational ImmunoMedicine, Catholic Research Institute of Medical Science, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID https://orcid.org/0000-0001-5715-3989

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies have reported the immunoregulatory effects of transplanting mitochondria from mesenchymal stem cells. However, whether similar effects can be achieved using mitochondria derived from human induced pluripotent stem cells (iPSCs; iMito) has not yet been investigated. Here, we examined the protective effects of iMito in a dextran sodium sulfate (DSS)-induced colitis mouse model. To address this, we investigated the effects both

Indexed as

FibrosisHuman induced pluripotent stem cellInflammatory bowel diseaseMitochondrial transplantationTh17/Treg homeostasis

Identifiers

PMID41523143
PMCPMC12780143

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.