Evidence map›Paper›PMID 41523131›Full record

ArticleTaiwan journal of ophthalmology

Liquiritigenin, a licorice-derived flavanone, reduces dry eye pathology via dual anti-inflammatory and antioxidant action.

Jeongho Kim, Soojin Yi, Sinsung Kang, Chegyem Yae, Jeong Mun Choi, Sang Bum Kim, Hong Kyun Kim

Abstract read
In one paragraph

Article in Taiwan journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeongho KimCell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, Korea.
Soojin YiCell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, Korea.
Sinsung KangDepartment of Biomedical Science, The Graduate School, Kyungpook National University, Daegu, Korea.
Chegyem YaeDepartment of Ophthalmology, Kyungpook National University Hospital, Daegu, Korea.
Jeong Mun ChoiDepartment of Ophthalmology, Kyungpook National University Hospital, Daegu, Korea.
Sang Bum KimDepartment of Ophthalmology, Kyungpook National University Hospital, Daegu, Korea.
Hong Kyun KimCell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLiquiritigenin (LIQ), an active flavanone derived from Glycyrrhiza uralensis, is known to possess potent antioxidant and anti-inflammatory properties. This study aimed to evaluate the antioxidative and anti-inflammatory effects of LIQ on experimental dry eye disease (DED) models. MATERIALS AND

methods

results

conclusionLIQ shows potential as a therapeutic agent for DED through its dual anti-inflammatory and antioxidative actions, primarily through modulation of the AKR superfamily.

Indexed as

Antioxidantsdry eye syndromesflavonoidsinflammationoxidative stress

Identifiers

PMID41523131
PMCPMC12782499

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.