ArticleJournal of pharmacy & bioallied sciences2025
Comparative Evaluation of the Efficacy of Triclosan-Coated and Chlorhexidine-Coated Suture on Bacterial Load Reduction in Periodontal Flap Surgery: A Clinicomicrobiological Study.
Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Background: Sutures are essential for wound closure but may facilitate microbial colonization, increasing the risk of surgical site infections. Antibacterial-coated sutures, such as triclosan (TCS) and chlorhexidine (CCS), have been developed to mitigate this concern. Materials and Methods: A double-blind, randomized clinical trial was conducted on 20 patients undergoing periodontal flap surgery, comparing TCS and CCS. Healing was assessed on postoperative day 8 using Landry's Healing Index; microbial burden was quantified through CFU enumeration and Gram staining. Results: Healing scores were comparable between groups (TCS: 4.1 ± 0.7; CCS: 3.9 ± 0.7; Conclusion: Chlorhexidine-coated sutures exhibited superior antimicrobial efficacy without compromising early wound healing.
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