ArticleJournal of pharmacy & bioallied sciences2025
Assessing the Efficacy of Garlic Pearls Combined with Lycopene Capsules on Mouth Opening in Oral Submucous Fibrosis Patients.
Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
Background and Aim: Oral submucous fibrosis (OSMF) is a debilitating premalignant condition affecting individuals across all age groups and both sexes. It is particularly prevalent in India and the South Asian subcontinent. Common clinical symptoms include reduced mouth opening and a burning sensation in the oral cavity. Materials and Methods: Study Design: Interventional Study Setting and Sample: This study was conducted at the outpatient department (OPD) of dental clinics and included patients clinically diagnosed with OSMF. A divider and scale were used to measure interincisal mouth opening at baseline and during follow-up intervals. Results: Intragroup comparisons revealed a statistically significant improvement in mouth opening over the 45-day treatment period. Improvement from Day 1 to Day 15 was significant ( Conclusion: The study demonstrated a significant improvement in mouth opening among OSMF patients treated with a 45-day regimen of lycopene capsules and garlic pearls. These findings highlight the therapeutic potential of this antioxidant-based combination in the management of OSMF.
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