ArticleJournal of pharmacy & bioallied sciences2025
Long-Term Outcomes of Dental Implants in Head and Neck Cancer Survivors Following Radiotherapy.
Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
Background: Dental implants have become a cornerstone in oral rehabilitation for head and neck cancer survivors. However, radiotherapy-integral to cancer treatment-can compromise bone quality, potentially affecting implant survival. Materials and Methods: A retrospective survey was conducted among 80 head and neck cancer survivors who received dental implants post-radiotherapy between 2010 and 2020 at two tertiary care centers. A structured questionnaire and follow-up clinical evaluation assessed implant survival, peri-implant conditions, and patient satisfaction. Key variables included radiation dose (>50 Gy or <50 Gy), time between radiotherapy and implant placement, and the use of adjunctive hyperbaric oxygen therapy (HBOT). Implant survival was defined as functional, pain-free implants without mobility or peri-implant radiolucency after a minimum 3-year follow-up. Results: Out of 250 dental implants placed in 80 irradiated patients, 212 implants (84.8%) survived beyond 5 years. Patients who received radiation doses <50 Gy showed a higher survival rate (91.2%) compared to those with >50 Gy (78.5%). The survival rate was significantly better in patients who waited more than 12 months before implant placement (90.5%) versus those with < 6 months interval (75.3%) ( Conclusion: Dental implants can provide favorable long-term outcomes in irradiated head and neck cancer patients, especially when radiation doses are moderate and implant placement is delayed post-therapy.
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