ArticleJournal of pharmacy & bioallied sciences2025
Evaluation of Hematological Changes in Type 2 Diabetes Mellitus and Their Correlation with Glycemic Control.
Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: T2DM is known to cause chronic hyperglycemia and results in a set of systemic complications. Hematological parameters, red cell indices testing, and platelet parameters in combination with white cell count may also become the parameters of inflammatory status and glycemic control. Materials and Methods: Patients diagnosed with T2DM were enrolled in a cross-sectional observational study with 120 subjects (90 diagnosed with T2DM and 30 age- and sex-matched controls). An automated hematology analyser was used to carry out complete blood counts (CBC). The measurements that were conducted on HbA1c used HPLC. The T2DM patients were divided into three groups based on glycemic control; there were good glycemic control (HbA1c 7.0% or less), moderate (HbA1c 7.1-8.5%), and poor control (HbA1c 8.5% or more). Results: The T2DM patients had a considerable increment in total leukocyte count (mean = 8.94 10 9/L) and neutrophil-to-lymphocyte ratio (NLR = 2.97) as compared with the controls (mean WBC = 6.21 10 9/L, NLR = 1.85). The mean platelet volume (MPV) value was higher in poorly-controlled diabetics (11.2 fL) than in the well-controlled ones (9.4 fL). There was a negative relationship between HbA1c and hemoglobin levels ( Conclusion: T2DM is linked with immense changes in blood and lab values, especially among those with mixed glycemic control. Higher WBC, MPV, and NLR indicate a low level of inflammation and hyperactivity of platelets, which might also be a risk factor that leads to complications of diabetes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.