ArticleJournal of pharmacy & bioallied sciences2025
Efficacy of Silver Diamine Fluoride and Nanosilver Fluoride in Preventing Caries: A Comparative Study.
Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
Funding
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Abstract
Background: Dental caries remains a prevalent global health issue, particularly among children. Silver diamine fluoride (SDF) is a well-established caries-arresting agent, while nanosilver fluoride (NSF), a newer formulation combining silver nanoparticles and fluoride, offers potential antibacterial and remineralizing benefits. However, comparative evidence on their caries-preventive efficacy remains limited. Methods: A randomized, double-blind, controlled clinical trial was conducted involving 90 caries-active children aged 6 to 9 years. Participants were randomly assigned to three groups ( Results: After 12 months, Group A (SDF) showed a mean increment of 0.8 ± 1.2 in DMFS, Group B (NSF) showed 1.1 ± 1.3, and Group C (control) showed 2.7 ± 1.5. The differences between Group A and Group C ( Conclusion: Both silver diamine fluoride and nanosilver fluoride were effective in preventing caries progression in high-risk children, with SDF showing marginally better efficacy. NSF appears to be a promising alternative with comparable outcomes.
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