ArticleJournal of pharmacy & bioallied sciences2025
Protocol for Effectiveness of Silver Diamine Fluoride in Arresting Caries in 3-6-year-old Children: A Community-Based Randomized Control Trial.
Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
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Abstract
Background: Early childhood caries is a significant public health issue in India, particularly in underserved rural and tribal communities. Silver diamine fluoride (SDF) has emerged as a noninvasive, low-cost treatment to arrest dental caries in young children. This study evaluates the effectiveness of 38% SDF compared to high-fluoride-releasing glass ionomer cement (GIC) in arresting active dentinal caries among preschool children attending Anganwadi Kendras in the Angara Block, Ranchi. Methods: A parallel-group, stratified cluster randomized controlled trial will be conducted over 24 months. A total of 400 children aged 3-6 years with the International Caries Detection and Assessment System (ICDAS) score of 5 or 6 active caries lesions will be recruited from 60 Anganwadi centres across six sectors in Angara Block, Ranchi. Children will be randomized at the Anganwadi cluster level into two groups: Group A (intervention) will receive 38% SDF and Group B (control) will receive high fluoride GIC restorations. Caries arrest will be evaluated using ICDAS criteria and visual-tactile assessment at 6, 12, 18, and 24 months. Expected Outcomes: The study anticipates that SDF will demonstrate comparable or superior efficacy in arresting caries relative to GIC in a community setting. Findings will support the use of SDF as a cost-effective, minimally invasive strategy suitable for integration into national oral health programs targeting young children in resource-constrained environments.
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