Evidence map›Paper›PMID 41522962›Full record

ArticleJournal of pharmacy & bioallied sciences2025

Analysis of Plant-Based and Herbal Therapies in Periodontal Treatment: Clinical Applications, Mechanistic Insights, and Efficacy.

Hiroj Bagde, Mallapragada Siddharth, Ashwini Dhopte, Vikas Singh, Mohammad Khursheed Alam, Sheetal Sharma

Abstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hiroj BagdePhD Scholar, School of Dental Sciences, Sharda University, Greater Noida, Uttar Pradesh, India.
Mallapragada SiddharthDepartment of Periodontology, School of Dental Sciences, Sharda University, Greater Noida, Uttar Pradesh, India.
Ashwini DhopteDepartment of Oral Medicine and Radiology, Chhattisgarh Dental College and Research institute, Chhattisgarh, India.
Vikas SinghDepartment of Public health Dentistry, Teerthanker Mahaveer Dental College and Research Centre, Teerthanker Mahavir University, Uttar Pradesh, India.
Mohammad Khursheed AlamDepartment of Preventive dentistry, College of Dentistry, Al Jouf University, Saudi Arabia.
Sheetal SharmaDepartment of Dentistry, Autonomous State Medical College, Pilibhit, Uttar Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontitis, a widespread chronic inflammatory disease, is primarily treated with scaling and root planing (SRP). However, plant-based adjunctive therapies, known for their anti-inflammatory, antimicrobial, and antioxidant effects, are emerging as valuable complements to SRP. This review presents findings from 24 studies on agents such as Edelweiss stem cells, pomegranate, neem, chamomile, and curcumin, which showed enhanced clinical outcomes in probing pocket depth (PPD) and clinical attachment levels (CAL) when used with SRP. These therapies offer safe and biocompatible alternatives to synthetic agents, potentially reducing antibiotic dependence and addressing antimicrobial resistance. The localized application of these agents maximizes periodontal benefits with minimal systemic exposure.

Indexed as

Anti-inflammatory agentsantioxidantsperiodontal pocketperiodontitisphytotherapyplant preparationstreatment outcome

Identifiers

PMID41522962
PMCPMC12788415

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.