Evidence map›Paper›PMID 41522946›Full record

ArticleJournal of pharmacy & bioallied sciences2025

Comparative Evaluation of Single-Flap Approach and Open-Flap Debridement with Calcium Phosphosilicate Bone Graft in the Treatment of Intrabony Defects: A Clinico-Radiographic Study.

Dimple Bhati, Amit Wadhawan, Prashant Tyagi, Manini Singh, Nidhi Yadav

Abstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Dimple BhatiDepartment of Periodontology, Shree Bankey Bihari Dental College and Research Centre, Ghaziabad, Uttar Pradesh, India.
Amit WadhawanDepartment of Periodontology, Shree Bankey Bihari Dental College and Research Centre, Ghaziabad, Uttar Pradesh, India.
Prashant TyagiDepartment of Periodontology, Shree Bankey Bihari Dental College and Research Centre, Ghaziabad, Uttar Pradesh, India.
Manini SinghDepartment of Periodontology, Shree Bankey Bihari Dental College and Research Centre, Ghaziabad, Uttar Pradesh, India.
Nidhi YadavDepartment of Periodontology, Shree Bankey Bihari Dental College and Research Centre, Ghaziabad, Uttar Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Periodontal intrabony defects pose a significant therapeutic challenge in periodontitis management. The single-flap approach (SFA) is a minimally invasive alternative to conventional open-flap debridement (OFD), aiming to improve healing outcomes and reduce surgical trauma. Aim: To compare the clinical and radiographic outcomes of SFA and OFD, both combined with calcium phosphosilicate (CPS) bone graft in the treatment of intrabony defects. Materials and Methods: This randomized clinical trial included 24 systemically healthy patients with chronic periodontitis and comparable intrabony defects. Patients were allocated into two groups: Group A (SFA + CPS putty) and Group B (OFD + CPS putty). Clinical parameters, including plaque index (PI), gingival index (GI), oral hygiene index-simplified (OHI-S), probing pocket depth (PPD), and relative attachment level (RAL), were measured at baseline, 3, 6, 9, and 12 months. Radiographic assessment using CBCT was conducted at baseline and 12 months to determine percentage bone fill. Results: Both techniques resulted in significant improvements. However, SFA showed superior reductions in PPD and better clinical attachment gain. Radiographically, the SFA group demonstrated significantly greater bone fill at 12 months ( Conclusion: SFA combined with CPS graft provides a less invasive and effective alternative to OFD, offering enhanced clinical outcomes and faster healing.

Indexed as

Bone regenerationCBCTCPS puttyintrabony defectopen-flap debridementperiodontitissingle-flap approach

Identifiers

PMID41522946
PMCPMC12788584

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