Evidence map›Paper›PMID 41522945›Full record

ArticleJournal of pharmacy & bioallied sciences2025

Effects of Various Chelating Agents in Combination with Sodium Hypochlorite on Root Fracture Toughness of Endodontically Treated Teeth after Ultrasonic Activation: An

Jishnu K Nair, Joy Mathew, Krishnan Hari, Binila S Babu, Feby Kuriakose, Alka Elza Prakash

Abstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jishnu K NairDepartment of Endodontics and Conservative Dentistry, Mar Baselios Dental College, Kothamangalam, Ernakulam, Kerala, India.
Joy MathewDepartment of Endodontics and Conservative Dentistry, Mar Baselios Dental College, Kothamangalam, Ernakulam, Kerala, India.
Krishnan HariDepartment of Endodontics and Conservative Dentistry, Mar Baselios Dental College, Kothamangalam, Ernakulam, Kerala, India.
Binila S BabuDepartment of Endodontics and Conservative Dentistry, Mar Baselios Dental College, Kothamangalam, Ernakulam, Kerala, India.
Feby KuriakoseDepartment of Endodontics and Conservative Dentistry, Mar Baselios Dental College, Kothamangalam, Ernakulam, Kerala, India.
Alka Elza PrakashDepartment of Endodontics and Conservative Dentistry, Mar Baselios Dental College, Kothamangalam, Ernakulam, Kerala, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objective: Various chelating compounds in combination with sodium hypochlorite were tested for their effects on root fracture toughness of ultrasonically activated endodontically treated teeth. Materials and Methods: Based on irrigant combination, 50 extracted lower premolar teeth were randomly assigned to five groups of 10. Group 1 (negative control), Group 2 (positive control), Group 3 (3% sodium hypochlorite [NaOCl] +17% ethylenediaminetetraacetic acid), Group 4 (3% NaOCl + 18% etidronic acid), and Group 5 (3% NaOCl + 10% citric acid). Ultrasound is used to activate irrigants. The obturated samples were tested using a universal testing machine for root fracture toughness. Results: It was found that endodontic treatment decreased root fracture toughness. Additionally, chelating agents reduce fracture resistance. This study found that 10% citric acid has the least effect on root dentin fracture resistance. Conclusion: Irrigation with various chelating agents and sodium hypochlorite reduces endodontic tooth fracture resistance. Citric acid was the most effective against fractures.

Indexed as

Chelating agentscitric acidfracture resistancesodium hypochloriteultrasonic activation

Identifiers

PMID41522945
PMCPMC12788554

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.