Evidence map›Paper›PMID 41522910›Full record

ArticleJournal of pharmacy & bioallied sciences2025

Efficacy of Emblica Officinalis and Curcumin Longa, Two Significant Herbal Antioxidants, in the Management of OSMF: A Comparative Cross-sectional Study.

Annette M Bhambal, Parnavi Mishra, Sudhanshu Saxena, Palak Jain Choudhary, Akshay K Agarwal, Aparna Raj

Abstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Annette M BhambalDepartment of Oral Medicine and Radiology, People's College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India.
Parnavi MishraDepartment of Oral Medicine and Radiology, People's College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India.
Sudhanshu SaxenaDepartment of Dentistry, MGM Medical College and Hospital, Jamshedpur, Jharkhand, India.
Palak Jain ChoudharyDepartment of Oral Medicine and Radiology, People's College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India.
Akshay K AgarwalDepartment of Oral Medicine and Radiology, People's College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India.
Aparna RajDepartment of Oral Medicine and Radiology, People's College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Oral submucous fibrosis (OSMF) is a persistent, potentially cancerous condition that affects 6.42 out of every 1000 people in South Asia. It causes burning sensation, limited mouth opening, and fibrosis. This study compares the efficacy of Emblica officinalis and Curcumin longa, two potent herbal antioxidants, in managing OSMF symptoms. Materials and Methods: Sixty clinically diagnosed OSMF patients were equally divided into Groups A and B who received Emblica officinalis and Curcumin longa respectively (i.e., twice daily for 2 months). Data was analyzed using the Chi-square and Student's paired Results: Group A showed greater reduction in oral burning (Visual Analogue Scale scores), while Group B exhibited significant improvement in mouth opening. Discussion: Curcumin longa was more effective in improving mouth opening and reducing fibrous bands, for treating OSMF-related structural and functional deficits. Emblica officinalis offered more relief from the burning sensation, indicating its importance in symptomatic therapy. Conclusion: A combination therapy may offer a more holistic approach. Future research should explore nanoparticle formulations of Curcumin longa and Emblica officinalis to enhance their therapeutic potential in OSMF and fibrosis.

Indexed as

Curcumin longaEmblica officinalismouth openingoral burningOSMF

Identifiers

PMID41522910
PMCPMC12788515

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