ArticleJournal of pharmacy & bioallied sciences2025
Retrospective Study on Various Surgical Approaches for Gastric Ulcer Perforation. A Comparative Study.
Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Gastric ulcer perforation remains a life-threatening emergency requiring timely surgical intervention. Multiple operative techniques exist, including primary closure, modified Graham's patch repair, gastrojejunostomy, and use of falciform ligament in cases of omental deficiency. Materials and Methods: A retrospective analysis was conducted from January 2020 to December 2024 involving 120 patients diagnosed with gastric ulcer perforation. The study included patients treated at both SRVS Medical College and a local private hospital. Based on intraoperative findings and surgeon preference, patients underwent one of the following surgical techniques: Group A ( Results: Group A showed shorter operative time (mean 55 ± 10 min) and hospital stay (mean 6 ± 2 days), but had a 15% rate of minor leakage. Group B had a leakage rate of 8.5%, with slightly longer operative time (mean 70 ± 12 min). Group C, used in giant perforations (>2 cm), had the longest operative time (mean 95 ± 15 min) but the lowest leak rate (4%), albeit with a prolonged hospital stay (mean 10 ± 3 days). Group D showed moderate outcomes with a 10% complication rate and hospital stay of 8 ± 2 days. Mortality was highest in Group A (2 cases), likely due to delayed presentation and peritonitis. Conclusion: Modified Graham's patch repair and gastrojejunostomy offer better outcomes in terms of leakage prevention and postoperative recovery compared to primary closure. The falciform ligament serves as a viable alternative in cases of omental deficiency.
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