Evidence map›Paper›PMID 41522634›Full record

ArticleImmunotherapy advances2026

The UK vaccine innovation pathway.

Sarah Danson, Robert P Jones, Kristina Duggleby, Gillian Rosenberg, Matthew Hallsworth, Maria Koufali

Abstract read
In one paragraph

Article in Immunotherapy advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sarah DansonDivision of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, United Kingdom.ORCID https://orcid.org/0000-0002-3593-2890
Robert P JonesUK Vaccine Innovation Pathway, National Institute for Health and Care Research, London, United Kingdom.
Kristina DugglebyUK Vaccine Innovation Pathway, National Institute for Health and Care Research, London, United Kingdom.
Gillian RosenbergNHS Cancer Programme, NHS England, London, United Kingdom.
Matthew HallsworthUK Vaccine Innovation Pathway, National Institute for Health and Care Research, London, United Kingdom.
Maria KoufaliUK Vaccine Innovation Pathway, National Institute for Health and Care Research, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer vaccines offer transformative potential in oncology, especially with advances in mRNA technologies. To accelerate advances in cancer vaccine research and capitalize on its COVID-19 vaccine leadership, the UK Government has launched the UK Vaccine Innovation Pathway (VIP) through a partnership between the National Institute for Health and Care Research (NIHR), NHS England, and pharmaceutical partners. Its innovative approaches to trial delivery have enabled a 500% increase in patient recruitment with 33 trials open or recently closed across 85 sites and 11 cancer types. Working alongside the Cancer Vaccine Launchpad (CVLP), which pre-screens patients across 55 NHS sites, VIP offers streamlined trial set-up, decentralized delivery, and equity-focused design. The UK's approach aligns scientific innovation with rapid clinical deployment, creating a scalable, patient-centred model for delivering individualized therapies. This article outlines the strategic framework, outcomes, and lessons from the VIP and CVLP to inform future national strategies in cancer vaccine deployment.

Indexed as

cancer vaccinesindividualized therapies

Identifiers

PMID41522634
PMCPMC12781866

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.