ArticlePakistan journal of medical sciences2025
Primary central nervous system lymphoma in children: Insights from the three-year experience at the largest public-sector pediatric oncology center in Pakistan.
Article in Pakistan journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Strengthening Academic Foundations: PINS' Journey Toward Research Excellence.Pakistan journal of medical sciences · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Primary CNS lymphoma (PCNSL) in children is a rare disease, and this study aimed to document the experience of dealing with this in our geographical and resource settings. Methodology: It was an ambidirectional cohort study conducted at the Department of Pediatric Hematology/Oncology and the Department of Pediatric Neurosurgery at the University of Child Health Sciences, The Children's Hospital Lahore, Pakistan from March 2024 to December 2024. This study included seven suspected and confirmed cases of PCNSL in children under the age of 16 years who presented to a public-sector specialized center in Pakistan over the three-year study period. Results: A total of seven cases of suspected PCNSL were included in the study. The median age at presentation was eight years, with a female-to-male ratio of 2.5:1. Most commonly presenting with a focal neurological deficit, with a median duration of symptoms of 12 weeks, and a median Lansky performance score of 50. Only 57% (04) of patients underwent surgical resection followed by adjuvant chemotherapy. Overall, 57% (03) of patients died, 29% (02) were lost to follow-up, and only 14% (01) are under treatment. Conclusion: PCNSL in children is equally rare in our part of the world, but has a dismal survival rate. Timely surgical intervention, improved supportive care, and a reduction in treatment abandonment might improve the prognosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.