ArticleTranslational andrology and urology2025
Exploring the association between the ZJU index and overactive bladder: a cross-sectional study based on NHANES 2011-2018.
Article in Translational andrology and urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Overactive bladder (OAB) is one of the most common urinary disorders, affecting approximately 16% of the global population. It is strongly associated with obesity, diabetes, and other metabolic risk factors. The ZJU index is an innovative computational tool that integrates body mass index (BMI), fasting blood glucose (FBG), triglycerides (TG), and the alanine aminotransferase (ALT) to aspartate aminotransferase (AST) ratio, and it is highly correlated with lipid metabolism. However, the relationship between the ZJU index and OAB has not been previously explored. This cross-sectional National Health and Nutrition Examination Survey (NHANES) analysis evaluates the ZJU index as a potential OAB predictive tool, informing early intervention strategies. Methods: This large-scale, cross-sectional study utilized data from the NHANES conducted between 2011 and 2018. Information on the medical history of renal OAB was obtained through questionnaires and recall interviews. The ZJU index was categorized into quartiles, and its association with OAB was examined using multivariate linear and logistic regression analyses, adjusted for potential confounders. The results were further visualized using restricted cubic splines (RCS) regression and threshold effect analysis. Subgroup and sensitivity analyses were also performed. Results: A total of 15,873 participants aged 20 years and older with complete data were included in the analysis. After controlling for confounding factors using logistic regression, a nonlinear relationship between the ZJU index and OAB was identified. Specifically, the prevalence of OAB increased with higher ZJU index levels [odds ratio (OR) =1.79, 95% confidence interval (CI): 1.57-2.04, P<0.001]. Subgroup analysis revealed that the association was significantly stronger in women (OR =1.03, 95% CI: 1.02-1.04, P<0.001), while no significant relationship was found in men (n=7,816; OR =1.01, 95% CI: 1.00-1.01, P=0.15). Conclusions: Our study demonstrates that the ZJU index is significantly associated with an increased risk of OAB, particularly in women. Further research is needed to confirm these findings and explore the underlying mechanisms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.