Evidence map›Paper›PMID 41522277›Full record

ArticleDiabetes spectrum : a publication of the American Diabetes Association2025

Population Screening for Type 1 Diabetes in Pediatrics via Well-Child Visits: Barriers and Facilitators to Implementation.

Christie Gilbert Klaczko, Nicole Walters, Alexis E Blackburn, Andrew Brangan, Gemme Campbell-Salome, Jessica Goehringer, Lakshmi Ilango, Michelle Pistner Nixon, Katrina M Romagnoli, Erin A Van Enkevort and 2 more

Abstract read
In one paragraph

Article in Diabetes spectrum : a publication of the American Diabetes Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Christie Gilbert KlaczkoDepartment of Genomic Health, Geisinger, Danville, PA.
Nicole WaltersDepartment of Genomic Health, Geisinger, Danville, PA.
Alexis E BlackburnGeisinger Commonwealth School of Medicine, Scranton, PA.
Andrew BranganDepartment of Genomic Health, Geisinger, Danville, PA.
Gemme Campbell-SalomeDepartment of Genomic Health, Geisinger, Danville, PA.
Jessica GoehringerDepartment of Genomic Health, Geisinger, Danville, PA.
Lakshmi IlangoGeisinger Commonwealth School of Medicine, Scranton, PA.
Michelle Pistner NixonBiostatics Service Core, Geisinger, Danville, PA.
Katrina M RomagnoliDepartment of Population Health Sciences, Geisinger, Danville, PA.
Erin A Van EnkevortDepartment of Population Health Sciences, Geisinger, Danville, PA.
Juliann M SavattDepartment of Genomic Health, Geisinger, Danville, PA.ORCID https://orcid.org/0000-0001-6444-1962
Laney K JonesDepartment of Genomic Health, Geisinger, Danville, PA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveScreening for type 1 diabetes provides an opportunity to identify those with presymptomatic, early-stage disease, enabling increased monitoring to prevent diabetic ketoacidosis and facilitating access to emerging therapies. Given potential benefits, discussions about population-wide type 1 diabetes screening are ongoing. Routine primary care visits could offer a scalable approach to such screening. We used mixed methods to explore multilevel barriers to and facilitators of type 1 diabetes autoantibody screening at well-child visits and, more broadly, the acceptability, appropriateness, and feasibility of such a screening approach. RESEARCH DESIGN AND

methodsSemi-structured interviews were completed with parents, clinicians, and health insurers. Transcripts were double coded using an iteratively adapted a priori codebook. A survey leveraging the validated Acceptability of Implementation, Intervention Appropriateness, and Feasibility of Intervention Measures instruments was deployed to assess pediatric primary care clinician perspectives.

resultsA total of 26 parents, 10 clinicians (endocrinologists and pediatricians), and two health insurers participated in interviews, and 15 pediatricians participated in the survey. Most parents interviewed and clinicians surveyed found type 1 diabetes screening acceptable and appropriate. Parents noted lack of education, need for a blood draw, costs, difficulty scheduling, and fear of results as barriers. Clinicians reported barriers including parental views on blood draws and clinician time. Insurers described lack of insurance coverage as a barrier. Facilitators across constituents included education, reduced costs, convenient screening, guidelines supporting screening, and institutional support.

conclusionIf population screening for type 1 diabetes is pursued, models that integrate primary care will be needed. Screening for type 1 diabetes through primary care well-child visits could enable high adoption if implementation strategies adequately address described barriers and promote facilitators.

Identifiers

PMID41522277
PMCPMC12784430

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.