ArticleJournal of ophthalmology2026
Effect of Preserved Versus Preservative-Free Artificial Tears on the Corneal Epithelial Thickness Mapping by MS-39 in Dry Eye Patients.
Article in Journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Contact Lens-Associated Ocular Surface and Corneal Disorders.Methods and protocols · 2026Review
- Effect of Preserved Versus Preservative-Free Artificial Tears on the Corneal Epithelial Thickness Mapping by MS-39 in Dry Eye Patients.Journal of ophthalmology · 2026Article
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Authors and funding
5 authors.
Funding
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Abstract
Purpose: To compare clinical and corneal epithelial changes between preservative and preservative-free artificial tear therapy using the MS-39 in patients with dry eye disease (DED). Methods: This prospective interventional comparative study included 88 eyes of 44 patients. Preserved artificial tears were given for the left eye (group A) and preservative-free artificial tears for the right eye (group B). They were evaluated before and 3 months after treatment using MS-39. The dry eye parameters and corneal epithelial thickness were recorded. Results: There was an increase in the NIBUT and improvement in the severity by OSDI score Conclusion: Although both preservative-free and preserved artificial tears show an increase in epithelial thickness using MS-39 and improvement in OSDI, preservative-free artificial tears show superiority, subjectively and objectively, compared to preserved artificial tears using even lighter preservatives, being a safer option for long-term application.
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