Evidence map›Paper›PMID 41522158›Full record

ArticleJournal of thoracic disease2025

Prevalence of

Edgar Amorín Kajatt, Herman Andres Perroud, Luis Garcia-Herreros, Francisco Suárez, Adrian Puello Guerrero, Luis Fernando Tejado Gallegos, Natalia Donner, Reto Huggenberger, Luis Corrales

Registry-linked trialAbstract read
In one paragraph

Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04742192 (A Multicountry, Multicentre, Non-interventional, Prospective Study to Determine the Prevalence of EGFR Mutations in Patients With Early-stage, Surgically Resected, Non-squamous, Non-small Cell Lung Cancer), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04742192 completednot on this map

A Multicountry, Multicentre, Non-interventional, Prospective Study to Determine the Prevalence of EGFR Mutations in Patients With Early-stage, Surgically Resected, Non-squamous, Non-small Cell Lung Cancer

TypeobservationalSponsorAstraZenecaRan2021 to 2022Enrolled601ConditionsNon-small Cell Lung Cancer
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Edgar Amorín KajattDepartment of Thoracic Surgical Oncology, National Institute of Neoplastic Diseases, Lima, Peru.
Herman Andres PerroudDepartment of Oncology, Sanatorio de la Mujer, Rosario, Argentina.
Luis Garcia-HerrerosDepartment of Thoracic Surgery, Santa Fé Foundation, Bogota, Colombia.
Francisco SuárezDepartment of Surgery, Santa María Clinic, Metropolitan Region, Chile.
Adrian Puello GuerreroDepartment of Medical Research, Rosa Emilia Sánchez Pérez de Tavares National Cancer Institute (INCART), Santo Domingo, Dominican Republic.
Luis Fernando Tejado GallegosAstraZeneca, Mexico City, Mexico.
Natalia DonnerAstraZeneca, Cambridge, UK.
Reto HuggenbergerAstraZeneca, Baar, Switzerland.
Luis CorralesDepartment of Medical Oncology, Center for Cancer Research and Management (CIMCA), San Jose, Costa Rica.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Although targeted and immune-based therapies are now recommended for early-stage non-small cell lung cancer (NSCLC), data on biomarker prevalence in Latin America (LATAM) remain limited. The aim of the descriptive, observational, real-world, EARLY-EGFR (NCT04742192) study was to determine the frequency of Methods: The LATAM subset prospectively enrolled patients with surgically resected stage IA-IIIB [American Joint Committee on Cancer (AJCC) 8th edition] non-squamous NSCLC from March 2021 to October 2022. Primary endpoint was Results: Of 80 patients (mean ± standard deviation age of 66.5±9.7 years) enrolled, 67.5% were females and 57.5% were never smokers. Most patients had pathological stage (PS) stage I (66.3%) NSCLC, with 85.0% patients having pN0; all patients had adenocarcinoma. Most patients (61.3%) had right lung involvement. More than one-third of patients (39.5%; 30/76) had Conclusions: The LATAM subset shows an

Indexed as

EGFR mutationsLatin America (LATAM)molecular profileNon-small cell lung cancer (NSCLC)stage I–III disease

Identifiers

PMID41522158
PMCPMC12780410

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.