Evidence map›Paper›PMID 41522093›Full record

ArticleCrystal growth & design2026

BEST-CSP Benchmark Study of Polymorphs I and II of Sulfamerazine and the Perils of Polytype Polymorphs.

William P Wood, Mihails Arhangelskis, Erika Bartůňková, Carlos E S Bernardes, A Daniel Boese, Doris E Braun, Dejan-Krešimir Bučar, Helena Butkiewicz, Ctirad Červinka, Bartolomeo Civalleri and 31 more

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Article in Crystal growth & design, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Best practices in `0 K' DFT energy calculations on molecular crystal structures.Acta crystallographica. Section C, Structural chemistry · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

41 authors.

William P WoodDepartment of Chemistry, University College London, 20 Gordon St, London WC1H 0AJ, U.K.ORCID https://orcid.org/0000-0003-3276-3638
Mihails ArhangelskisFaculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland.ORCID https://orcid.org/0000-0003-1150-3108
Erika BartůňkováInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague 6 160 00, Czech Republic.ORCID https://orcid.org/0009-0008-7374-5368
Carlos E S BernardesCentro de Química Estrutural, Institute of Molecular Sciences, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisboa, Portugal.ORCID https://orcid.org/0000-0003-1490-9728
A Daniel BoeseDepartment of Chemistry, University of Graz, Heinrichstrassse 28, Graz 8010, Austria.ORCID https://orcid.org/0000-0001-7388-778X
Doris E BraunUniversity of Innsbruck, Institute of Pharmacy, Pharmaceutical Technology, Josef-Moeller-Haus, Innrain 52c, A-6020 Innsbruck, Austria.ORCID https://orcid.org/0000-0003-0503-4448
Dejan-Krešimir BučarDepartment of Chemistry, University College London, 20 Gordon St, London WC1H 0AJ, U.K.ORCID https://orcid.org/0000-0001-6393-276X
Helena ButkiewiczFaculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland.ORCID https://orcid.org/0000-0001-7962-3603
Ctirad ČervinkaDepartment of Physical Chemistry, University of Chemistry and Technology, Prague, Technická 5, CZ-166 28 Prague 6, Czech Republic.ORCID https://orcid.org/0000-0003-1498-6715
Bartolomeo CivalleriDepartment of Chemistry, Via Pietro Giuria 7, 10125 Turin, Italy.ORCID https://orcid.org/0000-0003-3198-3161
Nicolas CouvratUniversity of Rouen Normandy, Normandy University, SMS laboratory (UR 3233), 76000 Rouen, France.ORCID https://orcid.org/0000-0002-5878-2696
Erik de RondeRadboud University Nijmegen, Institute for Molecules & Materials, Department of Solid State Chemistry, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands.ORCID https://orcid.org/0009-0002-9936-8333
Lorenzo DonàDepartment of Chemistry, Via Pietro Giuria 7, 10125 Turin, Italy.ORCID https://orcid.org/0000-0001-7735-3881
Martin DračínskýInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague 6 160 00, Czech Republic.ORCID https://orcid.org/0000-0002-4495-0070
Dzmitry FirahaAvant-Garde Materials Simulation, Alte Str. 2, Merzhausen 79249, Germany.ORCID https://orcid.org/0000-0002-6387-0754
Michal FulemDepartment of Physical Chemistry, University of Chemistry and Technology, Prague, Technická 5, CZ-166 28 Prague 6, Czech Republic.ORCID https://orcid.org/0000-0002-5707-0670
Reynaldo Geronia IiDepartment of Physical Chemistry, University of Chemistry and Technology, Prague, Technická 5, CZ-166 28 Prague 6, Czech Republic.
Natalia GoncharovaDepartment of Chemistry, University of Graz, Heinrichstrassse 28, Graz 8010, Austria.ORCID https://orcid.org/0009-0006-0797-0263
Marlena GrylJagiellonian University, Faculty of Chemistry, Gronostajowa 2, 30-387 Krakow, Poland.
Johannes HojaDepartment of Chemistry, University of Graz, Heinrichstrassse 28, Graz 8010, Austria.ORCID https://orcid.org/0000-0003-4138-2124
Anna HoserFaculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland.ORCID https://orcid.org/0000-0002-6799-3073
Joanna KrzeszczakowskaFaculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland.ORCID https://orcid.org/0000-0003-4624-0213
Alexander ListDepartment of Chemistry, University of Graz, Heinrichstrassse 28, Graz 8010, Austria.ORCID https://orcid.org/0000-0002-9782-2400
Ivor LončarićRuđer Bošković Institute, Bijenička Cesta 54, 10000 Zagreb Croatia.ORCID https://orcid.org/0000-0002-5554-4641
Bruno MladineoRuđer Bošković Institute, Bijenička Cesta 54, 10000 Zagreb Croatia.
Jonas NymanThe Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, U.K.
Edgar OlehovicsDepartment of Chemical Engineering, University College London, London WC1E 7JE, U.K.
Mattia RaimondoDepartment of Chemistry, Via Pietro Giuria 7, 10125 Turin, Italy.ORCID https://orcid.org/0009-0002-7064-1682
Ivo B RietveldUniversity of Rouen Normandy, Normandy University, SMS laboratory (UR 3233), 76000 Rouen, France.ORCID https://orcid.org/0000-0001-5987-3998
Rute I S RodriguesCentro de Química Estrutural, Institute of Molecular Sciences, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisboa, Portugal.
Luca RussoGSK Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K.ORCID https://orcid.org/0009-0002-3039-6379
Matteo SalvalaglioDepartment of Chemical Engineering, University College London, London WC1E 7JE, U.K.ORCID https://orcid.org/0000-0003-3371-2090
Mafalda SarraguçaLAQV, REQUIMTE, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal.ORCID https://orcid.org/0000-0003-0294-5596
Jiří ŠnajdrDepartment of Physical Chemistry, University of Chemistry and Technology, Prague, Technická 5, CZ-166 28 Prague 6, Czech Republic.
Vojtěch ŠtejfaDepartment of Physical Chemistry, University of Chemistry and Technology, Prague, Technická 5, CZ-166 28 Prague 6, Czech Republic.ORCID https://orcid.org/0000-0002-2839-8546
Guangxu SunXtalPi Inc (Shenzhen Jingtai Technology Co., Ltd.), International Biomedical Industrial Park (Phase II), 3F, 2 Hongliu Rd, Futian District, Shenzhen 518038, China.
Paul TinnemansRadboud University Nijmegen, Institute for Molecules & Materials, Department of Solid State Chemistry, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands.
Pamela S WhitfieldExcelsus Structural Solutions, Parkstrasse 1, 5234 Villigen, Switzerland.ORCID https://orcid.org/0000-0002-6569-1143
Zhuocen YangXtalPi Inc (Shenzhen Jingtai Technology Co., Ltd.), International Biomedical Industrial Park (Phase II), 3F, 2 Hongliu Rd, Futian District, Shenzhen 518038, China.ORCID https://orcid.org/0000-0002-3527-7240
Yizu ZhangXtalPi Inc (Shenzhen Jingtai Technology Co., Ltd.), International Biomedical Industrial Park (Phase II), 3F, 2 Hongliu Rd, Futian District, Shenzhen 518038, China.
Sarah L PriceDepartment of Chemistry, University College London, 20 Gordon St, London WC1H 0AJ, U.K.ORCID https://orcid.org/0000-0002-1230-7427

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the outcome of an interdisciplinary investigation, by the BEST-CSP network, of the kinetically favored form I and the low-temperature stable form II polymorphs of the drug sulfamerazine (SMZ). Form II can be reproducibly obtained by slurrying in acetonitrile-(MeCN)/water at room temperature, though seeding with form II significantly speeds up the conversion. New structure determinations have been obtained for both forms over a wide temperature range, with both single crystal and powder X-ray diffraction methods. Room temperature FT-IR and solid-state

Identifiers

PMID41522093
PMCPMC12784330

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