ArticleQuantitative imaging in medicine and surgery2026
Perioperative outcomes and survival of indocyanine green-guided minimally esophagectomy in patients with esophageal cancer: a retrospective comparison study.
Article in Quantitative imaging in medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: A growing body of clinical research has highlighted the potential of intraoperative fluorescence imaging for precise lymph node (LN) identification and dissection in esophageal cancer (EC). However, several issues remain. This study aimed to evaluate the safety and feasibility of indocyanine green (ICG)-guided LN dissection during radical esophagectomy in patients with esophageal squamous cell carcinoma (ESCC), while also assessing its long-term outcomes. Our findings provide a theoretical foundation for future research in this field. Methods: This retrospective cohort study included patients with ESCC who underwent surgical resection at a single center between November 2019 and November 2021. Univariable and multivariable Cox proportional hazard models were used to identify the prognostic factors associated with disease-free survival (DFS) and overall survival (OS). Data, including baseline patient characteristics, postoperative complications, quality of life scores, and survival outcomes, were collected through a comprehensive review of the clinical record system and patient-administered surveys. Results: The two groups were well-balanced in terms of the baseline characteristics [all P>0.05, except American Society of Anesthesiologists (ASA) classification, P=0.023]. Compared with the non-ICG group, the ICG group had significantly higher mean numbers of pathologically dissected LNs (15.1±1.6 Conclusions: ICG-guided LN dissection during minimally invasive EC surgery may contribute to improved DFS and OS in patients with ESCC.
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