Trial reportJournal of cosmetic dermatology2026
Reparative Effects of a Topical Antioxidant Serum Containing Vitamin C, Vitamin E, and Ferulic Acid After Ablative Fractional CO
Trial report in Journal of cosmetic dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Reparative Effects of a Topical Antioxidant Serum Containing Vitamin C, Vitamin E, and Ferulic Acid After Ablative Fractional COJournal of cosmetic dermatology · 2026Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
backgroundAblative fractional CO
aimsThe study aimed to evaluate the post-procedure reparative effects of a combination of vitamin C, E, and ferulic acid (CE Ferulic) in Chinese patients with atrophic acne scars.
methodsIn this randomized, investigator-blinded, split-face, controlled trial, patients aged 18-50 with moderate-to-severe atrophic acne scars were randomly assigned to apply CE Ferulic to intervention-side face and normal saline (NS) to control-side face, immediately after ablative CO
resultsSixty-four patients were included in the analysis. On Day 7, the intervention side showed a higher complete scab detachment rate than the control side (60.9% vs. 34.4%, p = 0.0026). EI and MI reduced significantly greater on the intervention side compared to the control side (Days 3, 7, and 14; p < 0.0001). On Day 14, the intervention side also demonstrated significantly better capability of maintaining skin hydration (p = 0.0367) and preventing TEWL (p = 0.0246) than the control side.
conclusionsThis study found that CE Ferulic led to enhanced wound healing, reduced erythema and melanin levels, and improved skin hydration following laser treatment, suggesting its beneficial application in combination with laser treatment to accelerate skin recovery.
trial registrationChiCTR2300078214.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.