Evidence map›Paper›PMID 41521554›Full record

ReviewNanomedicine (London, England)2026

Applications of fullerenes in the treatment of osteoarthritis.

Nicholas J Cormas, Kate G Johnson, Xudong Li, Li Jin

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nanomedicine (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nicholas J CormasDepartment of Orthopaedic Surgery, University of Virginia, Charlottesville, VA, USA.ORCID 0009-0006-9597-4853
Kate G JohnsonDepartment of Orthopaedic Surgery, University of Virginia, Charlottesville, VA, USA.
Xudong LiDepartment of Orthopaedic Surgery, University of Virginia, Charlottesville, VA, USA.ORCID 0000-0002-2688-740X
Li JinDepartment of Orthopaedic Surgery, University of Virginia, Charlottesville, VA, USA.ORCID 0000-0002-4322-8238

Funding

Macrophage Anchoring Nanomedicine to Replace Steroids for Intra-articular InjectionR21AR082052 · NIAMS · UNIVERSITY OF VIRGINIA · PI JIN, LI, LI, XUDONG J. · 2023 to 2024
$384k
NIAMS NIH HHS R21 AR082052
6 · The paper itself

Abstract

Osteoarthritis (OA) is a leading cause of disability among the elderly, yet no disease-modifying therapies are available. Oxidative stress, chronic inflammation, and progressive chondrocyte degeneration remain key therapeutic targets. Conventional anti-inflammatory drugs, such as steroids, offer transient relief but are rapidly cleared from the joint space. Nanomedicines have emerged as a promising strategy to overcome these limitations. Among nanomaterials, fullerenes (particularly C

Indexed as

Anti-Inflammatory AgentsFullerenesOsteoarthritisAnimalsAntioxidantsHumansInflammationNanomedicineOxidative StressAnti-Inflammatory AgentsAntioxidantsFullereneschondroprotectionfullerenesinflammationNanomedicineosteoarthritisoxidative stress

Identifiers

PMID41521554
PMCPMC12871392

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.