ArticleClinical endoscopy2026
Impact of body mass index on the outcomes of endoscopic retrograde cholangiopancreatography: a systematic review and network meta-analysis.
Article in Clinical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundObesity is an increasing health concern worldwide, and an elevated body mass index (BMI) may influence the outcomes of endoscopic retrograde cholangiopancreatography (ERCP). This systematic review and network meta-analysis aimed to investigate the association between BMI and ERCP outcomes.
methodsA systematic search was performed using PubMed, Scopus, and Web of Science to identify relevant studies that reported clinical outcomes of ERCP in different BMI groups. Patients were categorized into five BMI-based following groups: underweight (BMI<18.5 kg/m²), normal weight (18.5 kg/m²≤BMI<25 kg/m²), overweight (25 kg/m²≤BMI<30 kg/m²), obesity (30 kg/m²≤BMI<40 kg/m²), and morbid obesity (40 kg/m²≤BMI).
resultsAmong 3,001 unique citations, seven were included in the study. Meta-analysis revealed that obesity was not associated with an increased risk of post-ERCP pancreatitis (PEP) (odds ratio, 1.33; 95% confidence interval, 0.62-2.87). In the network analysis, none of the five BMI groups had a significantly higher risk of PEP than that of the other groups (p>0.05). Moreover, the BMI groups had similar rates of difficult cannulation, successful cannulation, complete stone extraction, and procedural success.
conclusionsERCP success and adverse events were similar among different BMI groups. Neither an elevated nor a low BMI was associated with an increased risk of PEP. Further large-scale prospective studies are required to validate these findings.
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