Evidence map›Paper›PMID 41521290›Full record

ArticleBMC anesthesiology2026

Optimized delivered oxygen concentration of a novel pediatric oxygen mask: a bench simulation study.

Yueh-Yin Chen, Nai-Ju Chan, Ya-Tin Lin, Tzu-Chun Kan, Pei-Jung Chang, Chun-Chun Hsu

Abstract read
In one paragraph

Article in BMC anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yueh-Yin Chen *School of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan.
Nai-Ju Chan *Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan.
Ya-Tin LinGraduate Institute of Metabolism and Obesity Sciences, College of Nutrition & TMU Research Center for Digestive Medicine, Taipei Medical University, Taipei, 110, Taiwan.
Tzu-Chun KanGenomics Research Center, Academia Sinica, Taipei, 115, Taiwan.
Pei-Jung ChangResearch Center of Digital Oral Science and Technology, College of Oral Medicine, Taipei Medical University, Taipei, 110, Taiwan.
Chun-Chun HsuSchool of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan. chunhsu@tmu.edu.tw.

Funding

National Science and Technology Council NSTC111-2628-B-038-018-MY3Taipei Medical University TMU112-5431-002-400
6 · The paper itself

Abstract

backgroundChildren have unique respiratory physiology, including low tidal volume, high respiratory rate, and low functional residual capacity, which often leads to dilution of inspired oxygen when using conventional oxygen masks. The SentriO Oxy™ mask is designed to provide a consistent, high oxygen concentration even at relatively low flow rates. This study evaluated its performance under simulated pediatric breathing conditions.

methodsA pediatric breathing simulator was used to test three respiratory rates [20, 30, 40 breaths per min (BPM)] and two tidal volumes (75 and 150 mL) at oxygen flow rates of 5 and 10 L/min, using either 600-mL or 1000-mL reservoirs. Oxygen concentration was continuously measured with a calibrated FlowAnalyser™. Five repeated trials were performed for each condition, and the maximum oxygen concentration was used for analysis.

resultsWith a 600-mL reservoir at 5 L/min, oxygen concentration decreased with higher respiratory rates. The 1000-mL reservoir delivered higher and more stable oxygen levels, particularly at 20 and 30 BPM. Increasing flow to 10 L/min improved oxygen delivery across reservoir sizes. The SentriO Oxy™ maintained ~ 80% oxygen concentration across most simulated pediatric breathing conditions.

conclusionsIn this bench simulation study, the SentriO Oxy™ provided high, stable oxygen concentrations across different pediatric breathing patterns, supporting its potential clinical usefulness in both acute and long-term pediatric oxygen therapy.

Indexed as

MasksOxygenOxygen Inhalation TherapyEquipment DesignHumansRespiratory RateTidal VolumeOxygenBreathing modelMedical deviceOxygen therapyPediatricPerformance evaluation

Identifiers

PMID41521290
PMCPMC12888703

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.