Evidence map›Paper›PMID 41521222›Full record

ArticleScientific reports2026

Isolation and quantification of polyphenolics, exploration of antioxidant, cytotoxicity, and wound healing activities of Pithecellobium dulce (Roxb.) Benth.

Alaa A Elhewehy, Ahlam M El-Fishawy, Rasha M Aly, Engy Mohsen, Marwa A A Fayed

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alaa A ElhewehyDepartment of Pharmacognosy, Faculty of Pharmacy, University of Sadat City, Sadat City, 32897, Egypt.ORCID http://orcid.org/0000-0001-9622-2932
Ahlam M El-FishawyPharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr El-Ainy Street, Cairo, 11562, Egypt.ORCID http://orcid.org/0000-0003-4925-7395
Rasha M AlyOrganic and Medicinal Chemistry Department, Faculty of Pharmacy, University of Sadat City, Sadat City, 32897, Egypt.
Engy Mohsen *Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr El-Ainy Street, Cairo, 11562, Egypt. engy.mohsen@pharma.cu.edu.eg.ORCID http://orcid.org/0009-0007-5723-9476
Marwa A A Fayed *Department of Pharmacognosy, Faculty of Pharmacy, University of Sadat City, Sadat City, 32897, Egypt. marwa.fayed@fop.usc.edu.eg.ORCID http://orcid.org/0000-0001-5609-7436

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pithecellobium dulce represent a valuable source of biologically active phytoconstituents. This study aimed to screen the methanolic extract for its different phytochemical classes, isolate the active principles from the ethyl acetate fraction, and conduct phenolic profiling using the HPLC-DAD technique. Additionally, the antioxidant, wound-healing, and cytotoxic activities were assessed in vitro. The molecular modelling (docking) studies are performed for the investigation of cervical and breast cancer cytotoxic activities for some isolated compounds. The extract phytochemical screening revealed the presence of flavonoids, alkaloids, anthraquinones, terpenes, sterols, tannins, saponins, carbohydrates, and reducing sugars. Kaempferol-3-O-rhamnoside (Afzelin) (1), fisetin 3-O-rhamnoside (2), and alangilignoside D (3) were isolated and identified from the ethyl acetate fraction using LC-MS,

Indexed as

Antineoplastic Agents, PhytogenicAntioxidantsFabaceaePlant ExtractsPolyphenolsWound HealingCell Line, TumorChromatography, High Pressure LiquidFlavonoidsHeLa CellsHumansMolecular Docking SimulationAntineoplastic Agents, PhytogenicAntioxidantsFlavonoidsPlant ExtractsPolyphenolsAfzelinFisetin 3-O-rhamnosideHPLC-DADLeguminosaeLignansP. dulce

Identifiers

PMID41521222
PMCPMC12795817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.