Evidence map›Paper›PMID 41521036›Full record

ArticleOrthopaedic surgery2026

Mid- to Long-Term Follow-Up Outcomes of Single Design Rotating Hinge Knee in Infected and Noninfected Revision Patients.

Zhisen Gao, Tiejian Li, Ti Zhang, Minzhi Yang, Yonggang Zhou, Wei Chai

Abstract read
In one paragraph

Article in Orthopaedic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhisen GaoChinese PLA Medical School, Beijing, China.
Tiejian LiChinese PLA Medical School, Beijing, China.ORCID https://orcid.org/0000-0002-3692-3419
Ti ZhangDepartment of Orthopedics, Peking University Third Hospital, Beijing, China.
Minzhi YangChinese PLA Medical School, Beijing, China.
Yonggang ZhouSenior Department of Orthopedics, The Fourth Medical Center of Chinese PLA General Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-7304-4691
Wei ChaiChinese PLA Medical School, Beijing, China.ORCID https://orcid.org/0000-0001-8781-9745

Funding

Beijing Science and Technology Plan 'AI+ Health Collaborative Innovation Cultivation' Z221100003522014Beijing Science and Technology Plan'AI+ Health Collaborative Innovation Cultivation' Z221100003522014
6 · The paper itself

Abstract

backgroundTotal knee arthroplasty (TKA) offers significant relief for advanced knee osteoarthritis. With an aging population, TKA procedures are increasing, leading to a higher demand for revision surgeries. Rotating-hinge knee (RHK) prostheses have emerged as a solution for complex revisions, but the long-term durability of RHK prostheses and their effectiveness in infection-related revisions remain controversial. Therefore, this study aimed to evaluate the mid- to long-term clinical and survivorship outcomes of a single-design rotating hinge knee (SDRHK) system in revision TKA, comparing patients revised for infection with those revised for noninfectious causes.

methodsThis retrospective study analyzed 110 patients who underwent revision total knee arthroplasty (rTKA) with a SDRHK system from 2004 to 2023, with an average follow-up of 11.3 years. Patients were divided into an infection group (n = 51) and a noninfection group (n = 59) for comparative analysis. Preoperative diagnostic arthrocentesis was performed to evaluate synovial cell count, leukocyte differential, and microorganisms. Functional outcomes were assessed using Hospital for Special Surgery (HSS) knee score, range of motion (ROM), and Knee Society Score (KSS). Study outcomes included prosthesis survival, mechanical failure, and complications. Data were analyzed using Kaplan-Meier survival analysis, t test, and χ

resultThe infection group experienced symptom onset significantly earlier than the noninfection group (18.8 vs. 50 months, p = 0.003), had a shorter initial prosthesis lifespan (32.7 vs. 66.8 months, p = 0.001), and underwent more surgeries before revision (2.6 vs. 1.6, p = 0.004). Microbiological analysis indicated that coagulase-negative staphylococci and Staphylococcus aureus were the most commonly isolated pathogens. The 5- and 10-year prosthesis survival rates in the infection group were 78.4% and 71%, respectively, while those in the noninfection group were 83.1% and 74.6%. At the latest follow-up, survival rates for the two groups were 68.6% and 71.2%, showing similar outcomes. Functional scores in both groups improved postoperatively, with no significant differences in HSS, ROM, or KSS scores between the groups.

conclusionThis study highlights the important value of RHK prostheses in the treatment of prosthetic joint infection (PJI) after TKA. Despite challenges such as earlier symptom onset, shorter prosthesis lifespan, and higher complication rates in the infection group, their functional outcomes and prosthesis survival rates were comparable to those of the noninfection group, further validating the effectiveness of RHK prostheses. These findings provide useful references for clinical management of PJI and underscore the importance of continued innovation in revision techniques.

Indexed as

Arthroplasty, Replacement, KneeKnee ProsthesisProsthesis-Related InfectionsReoperationAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleMiddle AgedProsthesis DesignProsthesis FailureRange of Motion, ArticularRetrospective StudiesTreatment Outcomelong‐term outcomesprosthetic joint infectionrevision total knee arthroplastyrotating hinge knee

Identifiers

PMID41521036
PMCPMC12862438

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.