Evidence map›Paper›PMID 41520330›Full record

Observational studyJournal of foot and ankle research2026

Morphological Changes and MRI Characteristics of the Achilles Tendon in Amateur Marathon Runners With Different Running Experience.

Wanzhen Yao, Yong Chen, Siyu Dai, Jing Zhou, Xinmiao Mao, Yanjing Zhang, Jianping Ding, Jie Liu, Jie Huang

Abstract readObservational Study
In one paragraph

Observational study in Journal of foot and ankle research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wanzhen YaoDepartment of Radiology, Hangzhou Normal University Affiliated Hospital, Hangzhou, Zhejiang, China.
Yong ChenDepartment of Radiology, Hangzhou Normal University Affiliated Hospital, Hangzhou, Zhejiang, China.
Siyu DaiFaculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Jing ZhouDepartment of Radiology, Hangzhou Normal University Affiliated Hospital, Hangzhou, Zhejiang, China.
Xinmiao MaoDepartment of Radiology, Hangzhou Normal University Affiliated Hospital, Hangzhou, Zhejiang, China.
Yanjing ZhangDepartment of Radiology, Hangzhou Normal University Affiliated Hospital, Hangzhou, Zhejiang, China.
Jianping DingDepartment of Radiology, Hangzhou Normal University Affiliated Hospital, Hangzhou, Zhejiang, China.
Jie LiuDepartment of Radiology, Hangzhou Normal University Affiliated Hospital, Hangzhou, Zhejiang, China.
Jie HuangDepartment of Radiology, Hangzhou Normal University Affiliated Hospital, Hangzhou, Zhejiang, China.ORCID https://orcid.org/0000-0002-4507-0243

Funding

Hangzhou Biomedicine and Health Industry Development Supporting Science and Technology Special Project 2024WJC012Hangzhou Medical and Health Science and Technology Project A20220387Hangzhou Medical and Health Science and Technology Project A20251077Hangzhou Medical and Health Science and Technology Project ZD20240006key medical Disciplines of Hangzhou YDYXZhejiang Province Medical and Health Science and Technology Programme 2022KY260
6 · The paper itself

Abstract

backgroundWith the escalating popularity of marathon running, Achilles tendon injuries, particularly gradual-onset Achilles tendon injury, have become common, often causing substantial training disruptions. However, the influence of running experience on the Achilles tendon structure in amateur runners remains largely unclear. This study aimed to investigate the association between running experience and asymptomatic Achilles tendon pathology as well as its structural changes.

methodsThis was a cross-sectional observational study. Forty-eight amateur marathon runners were categorized into four groups based on running experience (1, 3, 5, and > 5 years), with 12 healthy nonrunners as controls. Inclusion and exclusion criteria were strictly applied. All participants underwent MRI scanning using a 3.0 T GE scanner. Two radiologists evaluated MRI scans for pathology and measured tendon length, thickness, volume, and cross-sectional area (CSA). Statistical analyses, including Shapiro-Wilk, ANOVA, Kruskal-Wallis H, and chi-squared tests, were conducted using SPSS 23.0.

resultsBaseline characteristics showed no significant group differences. Qualitative analysis revealed that the prevalence of midportion tendinopathy, insertional tendinopathy, and retrocalcaneal bursitis increased significantly with longer running experience. Quantitative measurements indicated that tendon thickness, volume, and CSA were significantly greater in long-running groups compared to short-running and control groups, whereas tendon length remained unchanged. Interobserver reliability was excellent.

conclusionIn amateur marathon runners, running experience is associated with increased asymptomatic Achilles tendon pathology and morphological remodeling. Prolonged running may induce both adaptive and degenerative changes, highlighting the importance of MRI-based monitoring for early intervention in high-risk populations.

Indexed as

Achilles TendonMarathon RunningRunningAdultBursitisCross-Sectional StudiesFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedTendinopathyAchilles tendonmarathonmorphological changesMRIrunning experience

Identifiers

PMID41520330
PMCPMC12790804

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.