Evidence map›Paper›PMID 41520315›Full record

ArticleBioinformatics (Oxford, England)2026

Capturing gene-cell duality in a cat's cradle.

Anna Laddach, Fränze Progatzky, Vassilis Pachnis, Michael Shapiro

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anna LaddachNervous System Development and Homeostasis Laboratory, The Francis Crick Institute, London NW1 1AT, United Kingdom.ORCID 0000-0001-5552-6534
Fränze ProgatzkyNervous System Development and Homeostasis Laboratory, The Francis Crick Institute, London NW1 1AT, United Kingdom.
Vassilis PachnisNervous System Development and Homeostasis Laboratory, The Francis Crick Institute, London NW1 1AT, United Kingdom.
Michael ShapiroNervous System Development and Homeostasis Laboratory, The Francis Crick Institute, London NW1 1AT, United Kingdom.ORCID 0000-0002-2769-9320

Funding

Wellcome Trust FC001128Wellcome Trust FC001159
6 · The paper itself

Abstract

summaryCatsCradle is an R package for single-cell analysis that exploits the duality between cells and the genes they express. Our package provides tools to cluster genes, visualize relationships between them, and to explore relationships between gene clusters (programmes) and cell clusters (cell types). AVAILABILITY AND IMPLEMENTATION: CatsCradle is available freely as an R Bioconductor package (https://bioconductor.org/packages/CatsCradle) and interfaces directly with Seurat (Hao et al. 2024) and SingleCellExperiment (Amezquita et al. 2020) data structures.

Indexed as

Computational BiologySingle-Cell AnalysisSoftwareAnimalsMultigene FamilySingle-Cell Gene Expression Analysis

Identifiers

PMID41520315
PMCPMC12831930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.