Evidence map›Paper›PMID 41520087›Full record

ArticleMusculoskeletal surgery2026

Efficacy of blood flow restriction (BFR) rehabilitation treatment in patients undergoing primary total and partial knee arthroplasty: a single-center case-control study.

Simone Giusti, Biagio Zampogna, Vittorio Alfonsi, Simona Cerulli, Rocco Papalia, Ezio Adriani

Abstract read
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Article in Musculoskeletal surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Simone GiustiComplex Operational Unit of Sports Medicine & Joint Reconstruction, Agostino Gemelli University Polyclinic, Rome, Italy. simonegiustiwork@gmail.com.
Biagio ZampognaComplex Operational Unit of Trauma & Orthopaedic Surgery, Campus Bio-Medico University Hospital, Rome, Italy. b.zampogna@policlinicocampus.it.
Vittorio AlfonsiComplex Operational Unit of Sports Medicine & Joint Reconstruction, Agostino Gemelli University Polyclinic, Rome, Italy.
Simona CerulliComplex Operational Unit of Sports Medicine & Joint Reconstruction, Agostino Gemelli University Polyclinic, Rome, Italy.
Rocco PapaliaComplex Operational Unit of Trauma & Orthopaedic Surgery, Campus Bio-Medico University Hospital, Rome, Italy.
Ezio AdrianiComplex Operational Unit of Sports Medicine & Joint Reconstruction, Agostino Gemelli University Polyclinic, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBlood flow restriction (BFR) therapy has emerged as a promising rehabilitation modality to enhance post-operative recovery following knee arthroplasty. This study evaluates the efficacy of BFR rehabilitation in patients undergoing primary total and partial knee arthroplasty compared to standard physiotherapy protocols.

methodsA single-center, case-control study was conducted on patients undergoing knee arthroplasty. Participants were divided into two groups: one receiving conventional physiotherapy and the other incorporating BFR rehabilitation. Outcome measures included postoperative range of motion (ROM), quadriceps strength, functional mobility (assessed via the Timed Up and Go test), and patientreported pain and satisfaction scores.

resultsPatients in the BFR group demonstrated significantly greater improvements in quadriceps strength (p 0.05) and functional mobility compared to the control group. ROM and pain scores also showed favorable trends in the BFR group, indicating enhanced postoperative recovery. No significant adverse effects were reported.

conclusionsBFR rehabilitation appears to be an effective adjunct to conventional physiotherapy in enhancing functional recovery after knee arthroplasty. Further large-scale studies are warranted to validate these findings and optimize rehabilitation protocols.

Indexed as

ArthroplastyBFRRehabilitationTKRUKR

Identifiers

PMID41520087

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.