Evidence map›Paper›PMID 41520012›Full record

ArticleNPJ precision oncology2026

Survival prediction and risk stratification in R0-resected ovarian cancer: a multi-modal deep learning approach.

Yi Zhou, Yayang Duan, Mingda Teng, Siyao Li, Haonan Zhang, Fang He, Chuanfen Gao, Yun Xiong, Junli Wang, Xiangshan Fan and 1 more

Abstract read
In one paragraph

Article in NPJ precision oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yi Zhou *Department of Ultrasound, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Yayang Duan *Department of Ultrasound, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Mingda TengShanghai Key Laboratory of Data Science, School of Computer Science, Fudan University, Shanghai, China.
Siyao LiDepartment of Ultrasound, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Haonan ZhangDepartment of Ultrasound, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Fang HeDepartment of Ultrasound, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Chuanfen GaoDepartment of Ultrasound, The First Affiliated Hospital of Anhui Medical University, Gaoxin District, Hefei, Anhui, China.
Yun XiongShanghai Key Laboratory of Data Science, School of Computer Science, Fudan University, Shanghai, China.
Junli WangDepartment of Ultrasound, Second People's Hospital of Wuhu, Wuhu, Anhui, China.
Xiangshan FanDepartment of Pathology, The First Affiliated Hospital of Anhui Medical University, Gaoxin District, Hefei, Anhui, China.
Chaoxue ZhangDepartment of Ultrasound, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China. zcxay@163.com.

Funding

Clinical Natural Science Foundation of Anhui Medical University 2022xkj167Scientific research project of Anhui Provincial Health Commission AHWJ2023A30027
6 · The paper itself

Abstract

Ovarian cancer (OC) is a leading cause of gynecologic cancer mortality, with survival prediction limited by existing prognostic models that fail to capture tumor heterogeneity. Conventional methods lack precision for individualized risk assessment. Deep learning (DL) addresses these issues by integrating diverse data to improve survival prediction and risk stratification. This study introduces OvcaSurvivor, a novel multimodal DL framework for R0-resected OC patients, integrating whole-slide images (WSI), ultrasound (US), and clinical data from 543 patients. It uses advanced neural networks (CHIEF for WSI, ResNet50 for US) and an attention-guided fusion module. OvcaSurvivor showed superior performance, with C-indices of 0.81 (internal), 0.76 (external 1), and 0.70 (external 2). Time-dependent AUCs for 1-, 3-, and 5-year survival were highly accurate. WSI features drove prediction, and the model stratified patients into high/low-risk groups, highlighting clinical utility. This multimodal fusion advances OC precision oncology, enabling robust postoperative management.

Identifiers

PMID41520012
PMCPMC12886920

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.