Evidence map›Paper›PMID 41519956›Full record

ArticleNature communications2026

Closed-loop wearable neurostimulation system with triboelectric sensing to alleviate hemifacial spasms.

Xuecheng Qu, Jiahao Wan, Haohan Zhao, Shunyuan Xu, Xiangrong Cheng, Bo Yang, Zhibin Li, Linhong Ji, Jinting Wu, Zhou Li and 2 more

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xuecheng Qu *Medical Research Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
Jiahao Wan *State Key Laboratory of Tribology in Advanced Equipment, Department of Mechanical Engineering, Tsinghua University, Beijing, China.
Haohan Zhao *State Key Laboratory of Tribology in Advanced Equipment, Department of Mechanical Engineering, Tsinghua University, Beijing, China.
Shunyuan XuState Key Laboratory of Tribology in Advanced Equipment, Department of Mechanical Engineering, Tsinghua University, Beijing, China.
Xiangrong ChengState Key Laboratory of Tribology in Advanced Equipment, Department of Mechanical Engineering, Tsinghua University, Beijing, China.
Bo YangState Key Laboratory of Tribology in Advanced Equipment, Department of Mechanical Engineering, Tsinghua University, Beijing, China.
Zhibin LiState Key Laboratory of Tribology in Advanced Equipment, Department of Mechanical Engineering, Tsinghua University, Beijing, China.
Linhong JiState Key Laboratory of Tribology in Advanced Equipment, Department of Mechanical Engineering, Tsinghua University, Beijing, China.
Jinting WuDepartment of Neurosurgery, Tsinghua University Yuquan Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China. wujinting@mail.tsinghua.edu.cn.ORCID http://orcid.org/0009-0002-1639-8212
Zhou LiMedical Research Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China. li_zhou@mail.tsinghua.edu.cn.ORCID http://orcid.org/0000-0002-9952-7296
Jia ChengState Key Laboratory of Tribology in Advanced Equipment, Department of Mechanical Engineering, Tsinghua University, Beijing, China. chengjia@tsinghua.edu.cn.ORCID http://orcid.org/0000-0002-2557-0072
Chong LiMedical Research Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China. chongli@tsinghua.edu.cn.ORCID http://orcid.org/0000-0003-4340-7436

Funding

Beijing Nova Program 20230484288China Postdoctoral Science Foundation BX20230169, 2023M731943National Natural Science Foundation of China (National Science Foundation of China) No. 52405320
6 · The paper itself

Abstract

Hemifacial spasm (HFS) is a neurological disorder characterized by involuntary contractions of the facial muscles, which can significantly influence patients' quality of life. Traditional diagnostic methods are often subjective, and electromyography (EMG) monitoring is constrained by equipment limitations and interference. Current treatments include short-term Botulinum toxin (BTX) injections and high-risk microvascular decompression (MVD), both of which suffer from low patient compliance. This study introduces a closed-loop facial nerve stimulation system integrated into eyewear, featuring triboelectric sensors doped with butylated melamine formaldehyde (BMF)-CaCu

Indexed as

Electric Stimulation TherapyHemifacial SpasmWearable Electronic DevicesElectromyographyFacial MusclesFacial NerveFemaleHumansQuality of Life

Identifiers

PMID41519956
PMCPMC12790568

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.