ArticleNature communications2026
JULGI coordinates vascular development and leaf patterning through non-cell-autonomous regulation of miR165/166.
Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Dexamethasone-inducible LhGR/pOp system: simple and flexible spatiotemporal control of gene expression.Planta · 2026Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
The interplay between vascular development and leaf development is central to the evolutionary success of vascular plants, yet the underlying mechanisms remain poorly understood. Here, we identify the RNA-binding protein JULGI1 (JUL1) as a key integrator of vascular and leaf development in Arabidopsis. JUL1 is transcribed in leaf veins, while the protein distributes throughout the leaf, where it binds G-rich regions of pri-MIR165a transcripts on the abaxial side. This interaction disrupts hairpin formation and inhibits DICER-LIKE1 (DCL1)-mediated processing, reducing miR165/166 levels. Consequently, transcript levels of their targets, the Class III homeodomain leucine zipper (HD-ZIP III), increase, reinforcing adaxial-abaxial polarity. Our findings reveal a non-cell-autonomous mechanism by which vascular-derived JUL1 modulates miRNA biogenesis to coordinate leaf patterning with vascular development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.