ReviewJournal of translational medicine2026
Plant-derived exosome-like nanovesicles: dual-function platforms for anticancer therapy and drug delivery.
Review in Journal of translational medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Platycodon grandiflorus-Derived Nanovesicles Sensitize Gastric Cancer to T Cell Killing via Ferroptosis-Driven Membrane Mechanical Remodeling.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Extracellular vesicles for next-gen therapeutics and drug delivery.Molecular biomedicine · 2026Review
- MicroRNAs in Breast Cancer: Biological Functions and Technologies for Experimental and Therapeutic Applications.Cancers · 2026Review
- Review
- Plant-derived extracellular vesicles as emerging cardioprotective agents for cardiovascular diseases.Journal of nanobiotechnology · 2026Review
- Engineered Plant-Derived Extracellular Vesicles: A Novel Strategy for Tumor-Targeted Therapy.Pharmaceutics · 2026Review
- α-Helical peptides: design strategies and recent advances in biomedical applications.Journal of translational medicine · 2026Review
- Preparation ofBioengineering (Basel, Switzerland) · 2026Article
- Plant-Derived Extracellular-Vesicle-Like Particles: Immune Regulation and Disease Therapy.Research (Washington, D.C.) · 2026Review
- Plant-Derived Exosomes in Aesthetic Medicine.Biomaterials research · 2026Review
- Mechanistic Insights and Therapeutic Potential of Plant-Derived Exosome-Like Nanovesicles in Skin Tissue Regeneration.International journal of nanomedicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPlant-derived exosome-like nanovesicles (PDELNs) are nanoscale bilayered lipid vesicles secreted by plant cells that encapsulate a range of bioactive cargoes, including lipids, proteins, and nucleic acids. These vesicles play a crucial regulatory role in various pathophysiological processes. Owing to their natural origin, high biocompatibility, and low immunogenicity, PDELNs possess inherent advantages for biomedical use. MAIN BODY: They can function not only as intrinsic therapeutic agents but also as targeted drug delivery systems, allowing precise homing to disease sites and delivering combined therapeutic and carrier capabilities. This dual functionality enhances tumor-specific targeting and improves tissue penetration. PDELNs presents a versatile and integrated platform for cancer therapy, merging inherent therapeutic properties with intelligent delivery capabilities. This system demonstrates significant potential to overcome major limitations associated with conventional chemotherapy and existing nanomedicines. Given these multifaceted benefits, PDELNs have attracted growing interest as promising candidates for a wide range of biomedical applications. Herein, we systematically review and analyze recent literature on the applications of PDELNs in tumor therapy. This comprehensive overview encompasses the classification, biogenesis pathways, isolation and extraction methods, and therapeutic advantages of PDELNs, with a particular focus on its applications in oncology and its emerging role as a novel drug delivery system for cancer treatment.
conclusionsThis review aims to provide valuable insights and references to further advance the utilization of PDELNs in the management of neoplastic diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.