Evidence map›Paper›PMID 41519795›Full record

GuidelineItalian journal of pediatrics2026

Nutritional management of neonates who undergo major surgery for gastrointestinal disorders: a joint position paper of the Italian Society of Neonatology (SIN), the Italian Society of Pediatric Surgery (SICP), and the Italian Society of Pediatric Nutrition (SINUPE).

Domenico Umberto De Rose, Arianna Aceti, Nadia Liotto, Laura Morlacchi, Elena Maggiora, Simonetta Costa, Andrea Conforti, Maria Lorella Giannì, Maria Elisabetta Baldassarre, Giovanna Verlato and 12 more

Abstract readConsensus StatementPractice GuidelineReview
In one paragraph

Guideline in Italian journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Surgical Interventions for NEC-An Overview.Children (Basel, Switzerland) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Domenico Umberto De RoseNeonatal Intensive Care Unit, "Bambino Gesù" Children's Hospital IRCCS, Rome, Italy.
Arianna AcetiDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy. arianna.aceti2@unibo.it.ORCID http://orcid.org/0000-0001-9274-985X
Nadia LiottoNeonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Laura MorlacchiDivision of Neonatology, Woman and Child Department, "F. Del Ponte" Hospital, ASST-Settelaghi, Varese, Italy.
Elena MaggioraNeonatology Unit of the University, Sant'Anna Hospital, Città della Salute e della Scienza, Turin, Italy.
Simonetta CostaNeonatology and Neonatal Intensive Care Unit, Policlinico Casilino, Rome, Italy.
Andrea ConfortiNeonatal and Pediatric Surgery Unit, "Bambino Gesù" Children's Hospital IRCCS, Rome, Italy.
Maria Lorella GiannìNeonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Maria Elisabetta BaldassarreDepartment of Interdisciplinary Medicine, Neonatology and NICU Section, University "Aldo Moro", Bari, Italy.
Giovanna VerlatoNeonatal Intensive Care Unit, University Hospital of Padua, Padua, Italy.
Pasqua BettaAzienda Ospedaliera-Universitaria Policlinico Vittorio Emanuele, Presidio Ospedaliero Gaspare Rodolico, Catania, Italy.
Nunzia DecembrinoAzienda Ospedaliera-Universitaria Policlinico Vittorio Emanuele, Presidio Ospedaliero Gaspare Rodolico, Catania, Italy.
Alessandra ConsalesDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Carla OttavianoNeonatal Intensive Care Unit, "San Camillo Forlanini" Hospital, Rome, Italy.
Maria Grazia ScuderiAzienda Ospedaliera-Universitaria Policlinico Vittorio Emanuele, Presidio Ospedaliero Gaspare Rodolico, Catania, Italy.
Lorenza PutignaniMicrobiomics Unit, "Bambino Gesù" Children's Hospital IRCCS, Rome, Italy.
Giorgio FavaPediatric Surgery Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Luigi OrfeoNeonatal Intensive Care Unit, "Gemelli Isola - Isola Tiberina" Hospital, Rome, Italy.
Massimo AgostiDivision of Neonatology, Woman and Child Department, "F. Del Ponte" Hospital, ASST-Settelaghi, Varese, Italy.
Guglielmo Salvatori *Neonatal Intensive Care Unit, "Bambino Gesù" Children's Hospital IRCCS, Rome, Italy.
Irma Capolupo *Neonatal Intensive Care Unit, "Bambino Gesù" Children's Hospital IRCCS, Rome, Italy.
Collaborators of the Working Group on Nutrition of Surgical Newborn

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neonates undergoing major gastrointestinal surgery for congenital or acquired disorders require complex nutritional management to support their growth and recovery. Prolonged fasting can be detrimental, necessitating timely and appropriate nutritional support. This joint position paper by the Italian Society of Neonatology, the Italian Society of Pediatric Surgery, and the Italian Society of Pediatric Nutrition aims to provide evidence-based suggestions for the nutritional care of these vulnerable infants, addressing the lack of robust randomized controlled trials in this field through expert opinion. A panel of experts in neonatology, paediatric surgery, and paediatric nutrition across Italy reviewed the literature by searching the PubMed database (1990- September 2024) using specific keywords. English-language papers were analysed without restrictions on study design or outcomes. Identified references were cross-checked, and additional relevant literature was included based on expert knowledge. The panel formulated suggestions based on the available evidence and clinical expertise. The position paper provides specific suggestions for various aspects of nutritional management, including the timing and modalities of enteral nutrition (EN), the choice of milk (prioritizing human milk), vitamin and trace element supplementation, and condition-specific guidance for gastrointestinal disorders such as oesophageal atresia, congenital diaphragmatic hernia, chylothorax, intestinal atresia, abdominal wall defects, Hirschsprung disease, necrotizing enterocolitis, and intestinal failure. Early EN (within 48 hours post-surgery) is generally advised and then tailored according to feeding tolerance. The paper also emphasizes the importance of monitoring micronutrient deficiencies and promoting oral feeding skills. This joint position paper offers a comprehensive and multidisciplinary approach to the nutritional management of neonates undergoing major gastrointestinal surgery. Recognizing the limitations of current evidence, these suggestions aim to standardise and optimise nutritional care, based on available data and expert consensus, ultimately improving outcomes for this high-risk population. The paper highlights the need for individualised nutritional strategies, careful monitoring, and further research in this challenging area of neonatal care.

Indexed as

Digestive System Surgical ProceduresGastrointestinal DiseasesNutritional SupportEnteral NutritionHumansInfant, NewbornItalyNeonatologySocieties, Medical

Identifiers

PMID41519795
PMCPMC12895823

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.