ArticleBMC geriatrics2026
Impact of overweight and obesity on gastric and colorectal cancer incidence in the older adults: a nationwide cohort study.
Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Nationwide Big Data Studies of Endocrine Diseases Using the Korean National Health Information Database: Research Trends and Standardization of Operational Definitions.Endocrinology and metabolism (Seoul, Korea) · 2026Review
- Impact of kimura-takemoto atrophy classification on first-lineFrontiers in medicine · 2026Article
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11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn the era of population ageing, research on age-related diseases, including cancers in the older adults, is important. This study aims to evaluate the impact of obesity on the risk of gastric cancer (GC) and colorectal cancer (CRC), particularly in the older adults.
methodsThis is nationwide, population-based cohort study used on data from the Korean National Health Insurance Service (NHIS), including individuals aged ≥ 75 years who underwent national health screening between 2012 and 2015, followed-up until 2022. Risk factors and cumulative incidence curves for GC and CRC in this population were evaluated using the Fine-Gray method.
resultsAmong total of 1,353,658 individuals, 21,853 (1.93%) GC and 30,685 (2.72%) CRC were diagnosed during the follow-up. Compared to normal weight, individuals in the highest body mass index (BMI) category showed positive correlation with increased risks of GC, CRC, and composite cancer (GC + CRC; adjusted hazard ratio [95% confidence interval]: 1.113 [1.024–1.210], 1.212 [1.134–1.295], and 1.162[1.101–1.226] for GC, CRC, and composite cancer, respectively). In contrast, underweight individuals showed decreased risks of GC, CRC, and composite cancer (0.858 [0.803–0.917], 0.798 [0.751–0.846], and 0.825 [0.788–0.863], respectively). The cumulative incidence of GC and CRC was higher among individuals with overweight and class I obesity (BMI 25.0–29.99 kg/m2), particularly CRC. Furthermore, the co-existence of general obesity and abdominal obesity estimated using waist circumference was associated with an even greater risk of both GC and CRC.
conclusionsOverweight or obesity are modifiable risk factors for gastrointestinal cancers in the older adults. Maintaining a normal weight through appropriate weight control may have a beneficial effect on the prevention of gastrointestinal cancers in the older adults.
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