Evidence map›Paper›PMID 41519719›Full record

ArticleBMC neurology2026

Mobile Health Application for the Prevention of Stroke (MAPS): a pilot, single-arm study on an innovative health application designed for primary stroke prevention.

Matthias N Ungerer, Kilian Reichel, Manuel Feisst, Christine Tunkl, Benjamin Quenzer, Christoph Gumbinger

Abstract read
In one paragraph

Article in BMC neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matthias N UngererDepartment of Neurology, University Hospital Heidelberg, Heidelberg, Germany. matthias.ungerer@med.uni-heidelberg.de.
Kilian ReichelDepartment of Neurology, University Hospital Heidelberg, Heidelberg, Germany.
Manuel FeisstInstitute of Medical Biometry, Heidelberg University, Heidelberg, Germany.
Christine TunklDepartment of Neurology, University Hospital Heidelberg, Heidelberg, Germany.
Benjamin QuenzerNetzgut GmbH, Heidelberg, Germany.
Christoph GumbingerDepartment of Neurology, University Hospital Heidelberg, Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLong-term changes in healthy behavior are more likely when small improvements are made in daily health habits. Health applications can serve as cost-effective tools to help people adopt healthier lifestyles. In response to this need, we developed the MAPS app - an easy-to-use and innovative mobile health app for the primary prevention of stroke.

methodsWe conducted a prospective, pre-post, single-arm, multicomponent interventional pilot study over 6 months to evaluate the ability of the MAPS app to enhance healthy habits and reduce stroke risk factors among a healthy adult population recruited from an urban employer in Germany. Daily health habits were assessed using questionnaires at the beginning of the study, at 3 months, and at 6 months. We also measured estimated stroke risk over 5 and 10 years, as well as systolic blood pressure, Body Mass Index (BMI), abdominal circumference, LDL cholesterol, and HbA1c levels at the beginning and after 6 months.

resultsA total of 35 participants were recruited. One participant was lost to follow-up. Our analysis showed significant improvements in the daily health habits questionnaire after 6 months (mean change of 5.6 points; 95% confidence interval (CI) 3.20 to 7.95). We observed significant reductions in the estimated 5-year stroke risk (mean change - 0.3%; 95% CI -0.52 to -0.04), BMI (mean change - 0.6 kg/m²; 95% CI -1.17 to -0.02), and abdominal circumference (mean change - 2.8 cm; 95% CI -5.28 to -0.25). Changes in LDL cholesterol and HbA1c levels were not significant. Male participants tended to have lower initial scores on daily habit questionnaires, particularly in dietary health choices, and benefited more from participation in the study.

conclusionsOur results suggest that the MAPS app may help promote healthier daily habits and reduce stroke risk. While promising, these preliminary findings require further validation through larger randomized controlled trials. Additionally, they indicate potential gender-specific responses that need more investigation.

trial registrationThe study was registered retrospectively in the German Clinical Trials Register on 25th November 2024. (DRKSID DRKS00034491). Trial registration was submitted before enrollment started, but it was finalized after recruitment began due to technical issues.

Indexed as

Health BehaviorMobile ApplicationsPrimary PreventionStrokeAdultAgedFemaleGermanyHumansMaleMiddle AgedPilot ProjectsProspective StudiesRisk FactorsSurveys and QuestionnairesTelemedicineHabitsMobile applicationsPrimary prevention

Identifiers

PMID41519719
PMCPMC12853848

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.