Evidence map›Paper›PMID 41519707›Full record

SynthesisBMC ophthalmology2026

Which is better for myopia control in children: orthokeratology or DIMS spectacle lenses? A meta-analysis.

Desheng Song, Xiaoxue Chen, Fan Hong, Qing Zhou, Jiaqi Yao

Abstract readMeta-Analysis
In one paragraph

Synthesis in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Desheng SongDepartment of Ophthalmology, Children's Hospital of Nanjing Medical University, 72 Guangzhou Road, Nanjing, Gulou District, 210008, China.
Xiaoxue ChenDepartment of Nursing, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China.
Fan HongDepartment of Nursing, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China.
Qing ZhouDepartment of Ophthalmology, Children's Hospital of Nanjing Medical University, 72 Guangzhou Road, Nanjing, Gulou District, 210008, China. qingzhou112@sina.com.
Jiaqi YaoDepartment of Ophthalmology, Children's Hospital of Nanjing Medical University, 72 Guangzhou Road, Nanjing, Gulou District, 210008, China. l13221468@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to systematically evaluate the effectiveness of Defocus Incorporated Multiple Segments (DIMS) spectacle lenses compared with orthokeratology (Ortho-K) in controlling myopia.

methodsClinical studies related to DIMS and Ortho-K were searched for using PubMed, Medline, Embase, Ovid, CNKI, CBM, and Cochrane Library data up to August 2025. Following independent literature screening, data extraction, and risk of bias assessment by two researchers, analysis was conducted using RevMan 5.3 software.

resultsA total of nine studies were included in this analysis, all of which provided axial length (AL) changes at 1 year, while three studies reported spherical equivalent refraction (SER) changes. Pooled results indicated that the yearly increase of AL in the Ortho-K group was lower than that in the DIMS group (MD=-0.07, 95%CI (-0.11, -0.03), P < 0.001), with no statistically significant difference in SER changes between the two groups (MD = 0.05, 95%CI (-0.11, 0.22), P = 0.52). Subgroup analysis indicated that the comparative outcomes between Ortho-K and DIMS were influenced by ethnicity, sample size, and age (all P < 0.05).

conclusionOrtho-K demonstrates superior efficacy in controlling axial elongation compared to DIMS. However, ethnic and age factors should be considered when selecting between these two myopia control interventions.

Indexed as

EyeglassesMyopiaOrthokeratologic ProceduresRefraction, OcularAxial Length, EyeChildHumansDefocus incorporated multiple segments lensesMeta-analysisMyopiaOrthokeratology

Identifiers

PMID41519707
PMCPMC12882350

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.