Evidence map›Paper›PMID 41518538›Full record

ArticlePlant cell reports2026

SlMYB2: an R2R3-MYB transcription factor enhancing drought, salt, and cadmium tolerance in Solanum lycopersicum.

Shan Fu, Fei Liu, Ying Li, Chunyan Lu, Tiantian Liu, Songzhou Tian, Wei Jin, Pingan Guo, Liang Chen, Xinxin Geng

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Article in Plant cell reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Shan FuCollege of Life Sciences, Hubei Normal University, Huangshi, 435002, China.ORCID http://orcid.org/0000-0002-4970-7192
Fei LiuCollege of Life Sciences, Hubei Normal University, Huangshi, 435002, China.ORCID http://orcid.org/0009-0007-5947-7849
Ying LiCollege of Life Sciences, Hubei Normal University, Huangshi, 435002, China.ORCID http://orcid.org/0009-0002-9186-7576
Chunyan LuCollege of Life Sciences, Hubei Normal University, Huangshi, 435002, China.ORCID http://orcid.org/0009-0001-8728-5218
Tiantian LiuCollege of Life Sciences, Hubei Normal University, Huangshi, 435002, China.ORCID http://orcid.org/0009-0005-4967-7383
Songzhou TianCollege of Life Sciences, Hubei Normal University, Huangshi, 435002, China.ORCID http://orcid.org/0009-0007-9995-6115
Wei JinNo.1 Middle School of Macheng Hubei, Macheng, 438300, China.ORCID http://orcid.org/0009-0002-2897-845X
Pingan GuoCollege of Life Sciences, Hubei Normal University, Huangshi, 435002, China.ORCID http://orcid.org/0009-0005-4452-6543
Liang ChenCollege of Life Sciences, Hubei Normal University, Huangshi, 435002, China. chliang666@aliyun.com.ORCID http://orcid.org/0000-0002-4139-2253
Xinxin GengCollege of Life Sciences, Hubei Normal University, Huangshi, 435002, China. xxgeng@hbnu.edu.cn.ORCID http://orcid.org/0000-0001-6992-0532

Funding

Hubei Key Laboratory of Edible Wild Plants Conservation and Utilization EWPL202407Hubei Provincial College Students' innovation and Entrepreneurship Training Program S202510513084Natural Science Foundation of Hubei Province 2022CFB990
6 · The paper itself

Abstract

key messageSolanum lycopersicum SlMYB2 enhances drought, salt, and cadmium stress tolerance by upregulating stress-responsive genes, improving proline levels and antioxidant activity, and reducing oxidative damage. MYB transcription factors are widely present in plants and play critical roles in regulating responses to abiotic stresses, yet most remain poorly characterized. In this study, a typical R2R3-MYB gene (SlMYB2) from Solanum lycopersicum was isolated and identified, and its role in abiotic stress response was investigated. Stress-related cis-acting elements were present in the promoter sequence of SlMYB2, such as drought response elements, low-temperature response elements, and ABA response elements. Subcellular localization analysis showed that SlMYB2 is localized in the nucleus. Transactivation activity assay in yeast cells revealed that SlMYB2 has transactivation activity, and its active domain is located in the C-terminal. Drought, salt, and cadmium stress resulted in a rapid induction of SlMYB2 expression in tomato. Furthermore, compared to wild-type plants, SlMYB2-overexpressing Arabidopsis thaliana showed a higher seed germination rate and cotyledon greening rate, along with significantly increased proline content, chlorophyll levels, and peroxidase activity under drought, salt, and cadmium stress. In contrast, the transgenic lines exhibited a significantly lower malondialdehyde content than the wild-type. Expression analysis demonstrated that SlMYB2 overexpression upregulated key drought-, salt-, and cadmium-responsive genes under stress conditions, supporting its central role in the transcriptional regulation of integrated multi-stress tolerance in plants. These results indicated that SlMYB2 acts as a positive regulator in enhancing plant tolerance to drought, salt, and cadmium stress.

Indexed as

CadmiumPlant ProteinsSolanum lycopersicumTranscription FactorsArabidopsisDrought ResistanceDroughtsGene Expression Regulation, PlantPhylogenyPlants, Genetically ModifiedPromoter Regions, GeneticSalt ToleranceSodium ChlorideStress, PhysiologicalCadmiumPlant ProteinsSodium ChlorideTranscription FactorsCadmiumDroughtSaltSlMYB2Solanum lycopersicum

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.