Evidence map›Paper›PMID 41518278›Full record

SynthesisWound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society

Minimally Invasive Floating Metatarsal Osteotomy for Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis.

Arthur Tarricone, Collin E Pehde, Lee C Rogers, Allen Gee, Karla De La Mata, Kimberly Barron, Ian Barron, Alexandria A Armstrong, Robert Frykberg, Nitish Tirugnanasambandam and 1 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Minimally Invasive Floating Metatarsal Osteotomy for Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Arthur TarriconeDepartment of Orthopaedics, University of Texas at San Antonio, San Antonio, Texas, USA.ORCID https://orcid.org/0000-0001-5311-6283
Collin E PehdeDepartment of Orthopaedics, University of Texas at San Antonio, San Antonio, Texas, USA.
Lee C RogersDepartment of Orthopaedics, University of Texas at San Antonio, San Antonio, Texas, USA.
Allen GeeDepartment of Medicine, Mount Sinai Morningside and West Hospitals, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Karla De La MataDepartment of Orthopaedics, University of Texas at San Antonio, San Antonio, Texas, USA.
Kimberly BarronDepartment of Orthopaedics, University of Texas at San Antonio, San Antonio, Texas, USA.
Ian BarronDepartment of Orthopaedics, University of Texas at San Antonio, San Antonio, Texas, USA.ORCID https://orcid.org/0009-0005-9312-0857
Alexandria A ArmstrongDepartment of Orthopaedics, University of Texas at San Antonio, San Antonio, Texas, USA.
Robert FrykbergDepartment of Orthopaedics, University of Texas at San Antonio, San Antonio, Texas, USA.
Nitish TirugnanasambandamDepartment of Orthopaedics, University of Texas at San Antonio, San Antonio, Texas, USA.
Lawrence A LaveryDepartment of Orthopaedics, University of Texas at San Antonio, San Antonio, Texas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Minimally invasive floating metatarsal osteotomy has been proposed as a surgical strategy to address recurrent or persistent diabetic foot ulcers (DFUs) by correcting underlying biomechanical deformities. We conducted a systematic review and meta-analysis in accordance with PRISMA guidelines, querying four databases through September 2025 for studies involving adult patients with neuropathic DFUs treated with minimally invasive floating metatarsal osteotomy and followed for at least 12 months. Six studies comprising 184 subjects (176 with DFUs, 8 prophylactic) met inclusion criteria. Pooled outcomes demonstrated a healing rate of 98% (95% CI: 0.94-1.00) with a mean time to closure of 31.7 days (95% CI: 24.1-39.3). Ulcer recurrence occurred in 4% (95% CI: 0.02-0.09), while transfer lesions developed in 14% (95% CI: 0.08-0.20) and nonunion was observed in 14% (95% CI: 0.06-0.29). The overall infection rate was 7% (95% CI: 0.04-0.12). These findings indicate that minimally invasive floating metatarsal osteotomy is a safe and effective surgical option for off-loading neuropathic DFUs; demonstrating high healing rates, rapid time to closure and low recurrence when compared with conservative care. Larger randomised controlled trials are warranted to validate these results and establish standardised surgical indications.

Indexed as

Diabetic FootMetatarsal BonesMinimally Invasive Surgical ProceduresOsteotomyHumansTreatment OutcomeWound Healing

Identifiers

PMID41518278
PMCPMC12790268

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.