Evidence map›Paper›PMID 41518136›Full record

ReviewMovement disorders clinical practice2026

Voice and Speech in Atypical Parkinsonian Disorders.

Federico Rodriguez-Porcel, Farwa Ali, Michiko Bruno, Heather Davis Cuevas, Rohit Dhall, Kylie Dunne-Platero, Lawrence I Golbe, Ihtsham Haq, Nicole Herndon, Lawrence S Honig and 18 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Movement disorders clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Federico Rodriguez-PorcelDepartment of Neurology, Medical University of South Carolina, Charleston, South Carolina, USA.ORCID https://orcid.org/0000-0002-7492-5095
Farwa AliDepartment of Neurology, Mayo Clinic, Rochester, Minnesota, USA.
Michiko BrunoNeuroscience Institute, The Queen's Medical Center, University of Hawaii, Honolulu, Hawaii, USA.ORCID https://orcid.org/0000-0001-6575-424X
Heather Davis CuevasDepartment of Rehabilitation Services, University of North Carolina Health, Chapel Hill, North Carolina, USA.
Rohit DhallDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Kylie Dunne-PlateroDepartment of Rehabilitation Sciences, College of Health Professions, Medical University of South Carolina, Charleston, South Carolina, USA.
Lawrence I GolbeRutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
Ihtsham HaqDepartment of Neurology, University of Miami Miller School of Medicine, Miami, Florida, USA.
Nicole HerndonDepartment of Speech, Language, and Hearing Sciences, College of Public Health and Health Professions, University of Florida, Gainesville, Florida, USA.
Lawrence S HonigDepartment of Neurology, Taub Institute for Research on Alzheimer's Disease and Aging Brain, Columbia University Irving Medical Center, New York, New York, USA.
Kyurim KangDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0001-8061-4456
Sarah KremenNeurobehavior Program, Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Guillaume LamotteDepartment of Neurology, University of Utah, Salt Lake City, Utah, USA.
Nikolaus R McFarlandUF Health Norman Fixel Institute for Neurological Diseases, Gainesville, Florida, USA.ORCID https://orcid.org/0000-0002-8699-8857
Michela MirDepartment of Speech, Language, and Hearing Sciences, College of Public Health and Health Professions, University of Florida, Gainesville, Florida, USA.
Leila Montaser-KouhsariDepartment of Neurology, Brigham and Women Hospital, Harvard University, Boston, Massachusetts, USA.
Alexander PantelyatDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0002-6427-7485
Joel PageUF Health Norman Fixel Institute for Neurological Diseases, Gainesville, Florida, USA.
Hylan PickettSpeech-Language Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Laura Purcell VerdunVoicetrainer, LLC, Washington, District of Columbia, USA.
Kelly RichardsonDepartment of Rehabilitation Sciences, College of Health Professions, Medical University of South Carolina, Charleston, South Carolina, USA.
Jessica ShurerCurePSP, New York, New York, USA.
Michelle TrocheLaboratory for the Study of Upper Airway Dysfunction, Department of Biobehavioral Sciences, Teachers College, Columbia University, New York, New York, USA.
Rene L UtianskiDepartment of Neurology, Mayo Clinic, Rochester, Minnesota, USA.
Katya Villarreal-CavazosLaboratory for the Study of Upper Airway Dysfunction, Department of Biobehavioral Sciences, Teachers College, Columbia University, New York, New York, USA.
Tuhin VirmaniDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.ORCID https://orcid.org/0000-0002-1826-2020
Anne-Marie WillsDepartment of Neurology, Mass General Brigham, Boston, Massachusetts, USA.
as the Diagnosis and Treatment Working Group, CurePSP Center of Care (CoC) Network

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMotor speech disorders are early, common, and functionally limiting features of atypical parkinsonian disorders (APDs) such as progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), and multiple system atrophy (MSA). These impairments are underrecognized and undertreated in neurology clinics.

objectivesThis review aims to characterize speech impairment in APDs, offer practical guidance for clinical evaluation, highlight the role of Speech-Language pathologists (SLPs) in diagnosis and management, and outline current and emerging management strategies.

methodsA narrative review was conducted by the Diagnosis and Treatment Working Group of CurePSP's Centers of Care, integrating literature and clinical experience to summarize evaluation, diagnosis, and treatment of motor speech disorders in APDs.

resultsSpeech changes in APDs are often mixed dysarthrias with hypokinetic, spastic, and/or ataxic components, and may include apraxia of speech; these are frequently more severe and progress quicker than in Parkinson's disease. These features can assist in differential diagnosis and should prompt early referral to SLPs. Despite the high prevalence of speech and voice changes, comprehensive assessment of motor speech disorders is uncommon in neurology clinics. Current evidence regarding the efficacy of interventions is mixed. Digital acoustic analysis and neuromodulation offer promising directions for diagnosis and treatment.

conclusionsEarly, collaborative management of motor speech impairment elevates care in APDs. Neurologists and SLPs must work together to improve recognition, diagnosis, and care. Future research should focus on objective biomarkers and personalized therapies to support communication, autonomy, and quality of life for individuals living with APDs.

Indexed as

Corticobasal DegenerationMultiple System AtrophyParkinsonian DisordersSpeech DisordersSupranuclear Palsy, ProgressiveHumansapraxia of speechCorticobasal syndromedysarthriamultiple system atrophyprogressive supranuclear palsyspeechvoice

Identifiers

PMID41518136
PMCPMC13339587

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.