Evidence map›Paper›PMID 41518111›Full record

ArticleAmerican journal of human biology : the official journal of the Human Biology Council2026

Ecologies of Risk: Malaria and Settler Landscape Transformation in 19th-Century Ontario.

Amanda Cooke, Megan B Brickley

Abstract readHistorical Article
In one paragraph

Article in American journal of human biology : the official journal of the Human Biology Council, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Ecology of Malaria Mortality: A Spatiotemporal Mapping Approach.American journal of biological anthropology · 2026
    Article
  2. Ecologies of Risk: Malaria and Settler Landscape Transformation in 19th-Century Ontario.American journal of human biology : the official journal of the Human Biology Council · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Amanda CookeDepartment of Anthropology, McMaster University, Hamilton, Ontario, Canada.ORCID 0009-0001-2793-6488
Megan B BrickleyDepartment of Anthropology, McMaster University, Hamilton, Ontario, Canada.

Funding

Social Sciences and Humanities Research Council of Canada 752-2024-2545
6 · The paper itself

Abstract

objectivesThis study examines how settler-driven environmental change shaped malaria transmission and mortality in 19th-century southern Ontario. It aimed to understand the biosocial and ecological conditions that sustained endemic malaria in a temperate, colonial context. MATERIALS AND

methodsWe analyzed 2702 deaths attributed to probable malaria from 1831 to 1900 using civil, cemetery, parish, and municipal records. Each record was coded for age, sex, occupation, region, and season of death. To assess environmental influences, we incorporated monthly temperature and rainfall data from Toronto as a regional climate proxy. We examined demographic and spatial patterns at multiple scales, including towns, settlement type (urban/rural), and regional groupings, alongside temporal and seasonal variation. Statistical comparisons were used to explore associations, including nonlinear modeling of rainfall and malaria mortality.

resultsProbable malaria mortality declined over time but persisted throughout the century. Children under 5 accounted for over half of recorded deaths, while adults in agricultural occupations were also disproportionately affected. Rural areas, particularly in western Ontario, experienced the highest mortality. Generalized additive model (GAM) results indicated a strong nonlinear association between rainfall and malaria deaths (p < 0.001), while temperature was not a significant predictor.

conclusionsMalaria's persistence in 19th-century Ontario reflected a structural embedding of disease risk within settler-transformed landscapes. Deforestation, altered hydrology, and agricultural intensification created ecologies conducive to mosquito breeding. Vulnerability was not evenly distributed but shaped by age, labor, and proximity to altered environments. These findings underscore the importance of integrating environmental and historical data to reconstruct past disease ecologies and illustrate how evolutionary mismatch can drive vulnerability even in short-lived endemic contexts.

Indexed as

MalariaChildChild, PreschoolFemaleHistory, 19th CenturyHumansMaleOntarioRaincolonial healthenvironmental changeepidemiologyhistorical demographymalaria

Identifiers

PMID41518111
PMCPMC12801096

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.