Evidence map›Paper›PMID 41517919›Full record

ArticleJournal of cardiovascular electrophysiology2026

Navigating the Lead Paradox: Successful Co-Implantation of Cardiac Contractility Modulation Device and a Micra Leadless Pacemaker.

Gabriele Pavani, Paolo Garrone, Gianpaolo Varalda, Antonino Previti, Matteo Bianco, Alessandra Chinaglia

Abstract readCase Reports
In one paragraph

Article in Journal of cardiovascular electrophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gabriele PavaniCardiac Electrophysiology Unit, San Luigi Gonzaga University Hospital, Orbassano, Turin, Italy.ORCID 0009-0006-5318-4861
Paolo GarroneCardiac Electrophysiology Unit, San Luigi Gonzaga University Hospital, Orbassano, Turin, Italy.
Gianpaolo VaraldaCardiac Electrophysiology Unit, San Luigi Gonzaga University Hospital, Orbassano, Turin, Italy.
Antonino PrevitiCardiac Electrophysiology Unit, San Luigi Gonzaga University Hospital, Orbassano, Turin, Italy.
Matteo BiancoCardiology Department, San Luigi Gonzaga University Hospital, Orbassano, Turin, Italy.
Alessandra ChinagliaCardiac Electrophysiology Unit, San Luigi Gonzaga University Hospital, Orbassano, Turin, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWild-type transthyretin cardiac amyloidosis (ATTRwt-CA) can lead to refractory heart failure. A "lead paradox" occurs when patients with a Micra leadless pacemaker require lead-based Cardiac Contractility Modulation (CCM) therapy. CASE SUMMARY: We detail the first co-implantation of CCM and Micra devices in a 78-year-old male with ATTRwt-CA and NYHA III heart failure. A multi-view fluoroscopic technique ensured spatial separation, while specific device programming mitigated electrical crosstalk post-procedure.

conclusionAt 1 year, the patient stabilized to NYHA Class II without further hospitalizations. This dual-device strategy is a feasible and safe technical roadmap for this complex clinical problem.

Indexed as

Amyloid Neuropathies, FamilialCardiac Pacing, ArtificialCardiomyopathiesHeart FailureMyocardial ContractionPacemaker, ArtificialVentricular Function, LeftAgedEquipment DesignHeart RateHumansMaleTreatment Outcomecardiac amyloidosisCardiac Contractility Modulationcase reportdevice–device interactionelectrophysiology techniqueleadless pacemaker

Identifiers

PMID41517919
PMCPMC12891296

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.