Evidence map›Paper›PMID 41517132›Full record

ArticleFoods (Basel, Switzerland)2025

Low-Fat Cheddar Cheese Influences Gut Microbiota Composition and Diversity in Human Microbiota-Associated Mice.

Si Lu, Mairui Gao, Deepa Kuttappan, Mary Anne Amalaradjou

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Si LuDepartment of Animal Science, University of Connecticut, Storrs, CT 06269, USA.
Mairui GaoDepartment of Animal Science, University of Connecticut, Storrs, CT 06269, USA.
Deepa KuttappanDepartment of Animal Science, University of Connecticut, Storrs, CT 06269, USA.
Mary Anne AmalaradjouDepartment of Animal Science, University of Connecticut, Storrs, CT 06269, USA.ORCID 0000-0001-7411-2206

Funding

Foundation for Food and Agriculture Research New Innovator Award 430855
6 · The paper itself

Abstract

Cheese is a complex fermented dairy food containing bioactive nutrients and microorganisms that can influence host physiology. However, most existing evidence of its health effects derives from observational studies or investigations of isolated components rather than the whole food matrix. The present study examined the impact of low-fat Cheddar cheese as a whole food on the gut microbiota using a human microbiota-associated (HMA) mouse model. Germ-free C57BL/6 mice were colonized with human fecal microbiota and randomly assigned to either a control diet or a diet supplemented with low-fat Cheddar cheese (7.5%

Indexed as

16S rRNA sequencingBacteroidetesFirmicutesfunctional foodsgut microbiotahuman microbiota–associated micelactic acid bacterialow-fat cheddar cheesemicrobial diversityprobiotics

Identifiers

PMID41517132
PMCPMC12785681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.