Evidence map›Paper›PMID 41516915›Full record

ArticlePolymers2025

Novel Acrylic Bone Cement Containing Graphene Oxide: Synthesis and Characterization.

Luiz Fabiano Gomes Gularte, Guilherme Kurz Maron, Camila Perelló Ferrúa, Andressa da Silva Barboza, Tiago Fernandez Garcia, Geovanna Peter Correa, Cainá Corrêa do Amaral, Bruna Godinho Corrêa, Chiara das Dores do Nascimento, Everton Granemann Souza and 5 more

Abstract read
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Luiz Fabiano Gomes GularteGraduate Program in Health and Behavior, Catholic University of Pelotas, Pelotas 96015-560, Brazil.ORCID 0000-0003-2466-1367
Guilherme Kurz MaronGraduate Program in Science and Materials Engineering, Technology Development Center, Federal University of Pelotas, Pelotas 96010-610, Brazil.ORCID 0000-0003-4918-0383
Camila Perelló FerrúaGraduate Program in Health and Behavior, Catholic University of Pelotas, Pelotas 96015-560, Brazil.ORCID 0000-0001-8071-377X
Andressa da Silva BarbozaGraduate Program in Dentistry, Pelotas Dental School, Federal University of Pelotas, Pelotas 96015-560, Brazil.ORCID 0000-0001-9191-0672
Tiago Fernandez GarciaGraduate Program in Health and Behavior, Catholic University of Pelotas, Pelotas 96015-560, Brazil.ORCID 0000-0002-1951-3418
Geovanna Peter CorreaGraduate Program in Health and Behavior, Catholic University of Pelotas, Pelotas 96015-560, Brazil.ORCID 0000-0002-6397-9127
Cainá Corrêa do AmaralGraduate Program in Health and Behavior, Catholic University of Pelotas, Pelotas 96015-560, Brazil.ORCID 0000-0002-5603-5734
Bruna Godinho CorrêaGraduate Program in Health and Behavior, Catholic University of Pelotas, Pelotas 96015-560, Brazil.ORCID 0000-0002-3946-0632
Chiara das Dores do NascimentoGraduate Program in Science and Materials Engineering, Technology Development Center, Federal University of Pelotas, Pelotas 96010-610, Brazil.ORCID 0000-0001-6028-9852
Everton Granemann SouzaGraduate Program of Electronic and Computer Engineering, Catholic University of Pelotas, Pelotas 96015-560, Brazil.ORCID 0000-0001-9884-6626
Cesar AguzzoliExact Sciences and Engineering, University of Caxias do Sul, Caxias do Su 95070-560, Brazil.ORCID 0000-0001-9122-4461
Neftali Lenin Villarreal CarreñoGraduate Program in Science and Materials Engineering, Technology Development Center, Federal University of Pelotas, Pelotas 96010-610, Brazil.ORCID 0000-0002-5780-817X
Juliana Silva Ribeiro de AndradeGraduate Program in Dentistry, Pelotas Dental School, Federal University of Pelotas, Pelotas 96015-560, Brazil.ORCID 0000-0002-6847-6262
Rafael Guerra LundGraduate Program in Science and Materials Engineering, Technology Development Center, Federal University of Pelotas, Pelotas 96010-610, Brazil.ORCID 0000-0003-1006-3809
Fernanda NedelGraduate Program in Health and Behavior, Catholic University of Pelotas, Pelotas 96015-560, Brazil.ORCID 0000-0002-9055-8328

Funding

Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul 23/2551-0000511-5National Council for Scientific and Technological Development 409092/2022-3
6 · The paper itself

Abstract

Polymethylmethacrylate (PMMA) bone cement is widely used in orthopedics, accounting for approximately 80% of knee joint replacements in the United States. While prosthesis designs and materials have evolved to improve performance and durability, PMMA cement has undergone minimal compositional changes. Carbon-based nanomaterials, particularly graphene oxide (GO), have attracted interest for their ability to enhance the mechanical and thermal properties of orthopedic cements. This study evaluated the effects of incorporating different GO concentrations into PMMA bone cement on its mechanical properties, cytocompatibility, and antibacterial activity. PMMA was modified with GO at 0.1, 0.25, and 0.5 weight percent (wt%) for mechanical and antibacterial tests, and at 1.0 wt% for cytocompatibility. Mechanical performance was assessed via four-point bending tests. Cytocompatibility was evaluated using mouse embryonic fibroblasts (NIH/3T3), and antibacterial activity was tested against

Indexed as

anti-bacterial agentsbiocompatible materialsbone cementsgraphene oxidepolymethyl methacrylate

Identifiers

PMID41516915
PMCPMC12787345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.