A Heptamethine Cyanine-Based Near-Infrared Optical Sensor for Copper(II) Detection in Aqueous Solutions and Living Cells.

Ziya Aydin, Bing Yan, Maolin Guo

Abstract read

In one paragraph

Article in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ziya AydinDepartment of Chemistry and Biochemistry and UMass Cranberry Health Research Center, University of Massachusetts Dartmouth, 285 Old Westport Road, Dartmouth, MA 02747, USA.

Bing YanDepartment of Chemistry and Biochemistry and UMass Cranberry Health Research Center, University of Massachusetts Dartmouth, 285 Old Westport Road, Dartmouth, MA 02747, USA.

Maolin GuoDepartment of Chemistry and Biochemistry and UMass Cranberry Health Research Center, University of Massachusetts Dartmouth, 285 Old Westport Road, Dartmouth, MA 02747, USA.

Funding

National Science Foundation (US) CHE-1213838 and CHE-1229339

6 · The paper itself

Abstract

Copper ions are essential trace elements that play critical roles in redox reactions, signal transduction, energy metabolism, and regulation of the central nervous system. However, excess copper can induce cytotoxicity and contribute to various pathological conditions, highlighting the need for sensitive and selective detection methods. We report a novel near-infrared (NIR) optical sensor, IRPhen, based on a heptamethine cyanine scaffold conjugated with a 1,10-phenanthroline Cu

Indexed as

Biosensing TechniquesCarbocyaninesCopperWaterFluorescent Chemosensor CompoundsFluorescent DyesHumansHydrogen-Ion ConcentrationPhenanthrolinesSolutionsSpectroscopy, Near-Infrared1,10-phenanthrolineCarbocyaninesCopperFluorescent Chemosensor CompoundsFluorescent Dyesheptamethine cyanine dyePhenanthrolinesSolutionsWater1,10-phenanthrolinebio-imagingcopper detectionfluorescentheptamethine cyaninenear-infrared (NIR)optical sensor

Identifiers

PMID41516565

DOI10.3390/s26010130

PMCPMC12787501

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.