Evidence map›Paper›PMID 41516401›Full record

ReviewInternational journal of molecular sciences2026

Specific Recognition of Glycoproteins: Design Strategies and Application Prospects of Molecularly Imprinted Polymers.

Ping Xie, Zi-Ying Chen, Chun-Fang Xie, Jie-Ping Fan

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ping XieDepartment of Chemical Engineering, School of Chemistry and Chemical Engineering, Nanchang University, Nanchang 330031, China.
Zi-Ying ChenDepartment of Chemical Engineering, School of Chemistry and Chemical Engineering, Nanchang University, Nanchang 330031, China.ORCID 0009-0005-8931-6662
Chun-Fang XieDepartment of Chemical Engineering, School of Chemistry and Chemical Engineering, Nanchang University, Nanchang 330031, China.ORCID 0000-0002-2812-1459
Jie-Ping FanDepartment of Chemical Engineering, School of Chemistry and Chemical Engineering, Nanchang University, Nanchang 330031, China.

Funding

National Natural Science Foundation of China 22478171Natural Science Foundation of Jiangxi Province 20242BAB20113Natural Science Foundation of Jiangxi Province KJ202410090184Support Plan of Ganpo Outstanding Talents-Provincial High-level and Urgently Needed Overseas Talent Introduction Program 20232BCJ25076
6 · The paper itself

Abstract

Glycoproteins pose significant challenges for specific recognition due to their structural complexity and microheterogeneity. Molecularly imprinted polymers (MIPs) have emerged as promising synthetic receptors, offering high stability and tailorable recognition sites. This review specifically highlights and systematically evaluates several cutting-edge design strategies tailored for glycoproteins, including oriented surface imprinting for site-accessible recognition, epitope imprinting for enhanced specificity, and post-imprinting modification for tailored functionality. The fundamental principles, technical advantages, and applications in glycoprotein detection and separation are thoroughly discussed, with a particular emphasis on a comparative analysis to guide strategy selection and how they collectively address the persistent challenges of traditional imprinting. Future perspectives highlight stimuli-responsive systems, multimodal recognition, and computational design to advance MIPs as indispensable tools in proteomics and personalized medicine. The synergistic integration of these advanced strategies within sustainable and standardized MIP systems is particularly promising for fabricating next-generation synthetic receptors with enhanced recognition capabilities.

Indexed as

GlycoproteinsMolecular ImprintingMolecularly Imprinted PolymersAnimalsEpitopesHumansPolymersEpitopesGlycoproteinsMolecularly Imprinted PolymersPolymersepitope imprintingglycoproteinsmolecularly imprinted polymersoriented surface imprintingpost-imprinting modificationspecific recognition

Identifiers

PMID41516401
PMCPMC12787181

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.