Evidence map›Paper›PMID 41516362›Full record

ReviewInternational journal of molecular sciences2026

GJB2-Related Hearing Loss: Genotype-Phenotype Correlations, Natural History, and Emerging Therapeutic Strategies.

Julia Anne Morris, Tomas Gonzalez, Susan H Blanton, Simon Ignacio Angeli, Xue Zhong Liu

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julia Anne MorrisDepartment of Otolaryngology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.ORCID 0009-0007-3766-5611
Tomas GonzalezDepartment of Otolaryngology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Susan H BlantonDepartment of Otolaryngology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.ORCID 0000-0002-5433-3439
Simon Ignacio AngeliDepartment of Otolaryngology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Xue Zhong LiuDepartment of Otolaryngology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.ORCID 0000-0002-4758-6470

Funding

Molecular Genetics on Non Syndromic Hearing Loss (NSHL)R01DC005575 · NIDCD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LIU, XUE Z · 2001 to 2024
$10.6M
Miami Otolaryngology Surgeon-Scientist Training Program (MOSSTP)R25DC020726 · NIDCD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Christine Thuyvan Dinh · 2023 to 2026
$988k
Development of human inner ear organoid platforms for human auditory/vestibular disordersR01DC022239 · NIDCD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LIU, XUE Z · 2025 to 2025
$767k
National Institute of Health USA NIDCD R25 DC020726 (JAM)NIDCD NIH HHS R01 DC005575NIDCD NIH HHS R01 DC022239NIDCD NIH HHS R25 DC020726NIH USA R01DC005575NIH USA R01DC022239NIH USA R01DC107624NIH USA RH220053- W81XWH-22-HRRP-FRA
6 · The paper itself

Abstract

This review integrates molecular, clinical, and translational data to provide an updated understanding of

Indexed as

Connexin 26ConnexinsGenetic Association StudiesHearing LossAnimalsGenetic TherapyHumansMutationPhenotypeConnexin 26ConnexinsGJB2 protein, humancochlear implant outcomescongenital hearing lossconnexin-26gene therapygeneticsgenotype-phenotype correlationsGJB2natural historynon-syndromic hearing loss

Identifiers

PMID41516362
PMCPMC12787082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.